Evidence map›Paper›PMID 36296720›Full record

ArticleMolecules (Basel, Switzerland)2022

Synthesis, In Vitro Anti-Microbial Analysis and Molecular Docking Study of Aliphatic Hydrazide-Based Benzene Sulphonamide Derivatives as Potent Inhibitors of α-Glucosidase and Urease.

Shoaib Khan, Shahid Iqbal, Mazloom Shah, Wajid Rehman, Rafaqat Hussain, Liaqat Rasheed, Hamad Alrbyawi, Ayed A Dera, Mohammed Issa Alahmdi, Rami Adel Pashameah and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
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  8. Dysregulated Liver Metabolism and Polycystic Ovarian Syndrome.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 2 countries.

Shoaib KhanDepartment of Chemistry, Hazara University, Mansehra 21120, Pakistan.
Shahid IqbalDepartment of Chemistry, School of Natural Sciences (SNS), National University of Science and Technology (NUST), H-12, Islamabad 46000, Pakistan.ORCID 0000-0002-4607-6217
Mazloom ShahDepartment of Chemistry, Abbottabad University of Science and Technology (AUST), Abbottabad 22010, Pakistan.
Wajid RehmanDepartment of Chemistry, Hazara University, Mansehra 21120, Pakistan.
Rafaqat HussainDepartment of Chemistry, Hazara University, Mansehra 21120, Pakistan.
Liaqat RasheedDepartment of Chemistry, Hazara University, Mansehra 21120, Pakistan.
Hamad AlrbyawiPharmaceutics and Pharmaceutical Technology Department, College of Pharmacy, Taibah University, Medina 42353, Saudi Arabia.ORCID 0000-0003-0820-3884
Ayed A DeraDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha 61413, Saudi Arabia.ORCID 0000-0002-6248-8983
Mohammed Issa AlahmdiDepartment of Chemistry, Faculty of Science, University of Tabuk, Tabuk 71491, Saudi Arabia.
Rami Adel PashameahDepartment of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah 24230, Saudi Arabia.
Eman AlzahraniDepartment of Chemistry, College of Science, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Abd-ElAziem FaroukDepartment of Biotechnology, College of Science, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Hazara University · PKTaif University · SAAbbottabad University of Science and Technology · PKKing Khalid University · SANational University of Sciences and Technology · PKTaibah University · SAUmm al-Qura University · SAUniversity of Tabuk · SA

Funding

King Khalid University GRP/242/43Umm al-Qura University 22UQU4320141DSR78
6 · The paper itself

Abstract

A unique series of sulphonamide derivatives was attempted to be synthesized in this study using a new and effective method. All of the synthesized compounds were verified using several spectroscopic methods, including FTIR,

Indexed as

alpha-GlucosidasesUreaseAcarboseBenzeneBenzene DerivativesEnzyme InhibitorsGlycoside Hydrolase InhibitorsHydrazinesMolecular Docking SimulationMolecular StructureStreptomycinStructure-Activity RelationshipSulfanilamideThioureaAcarbosealpha-GlucosidasesBenzeneBenzene DerivativesEnzyme InhibitorsGlycoside Hydrolase InhibitorsHydrazinesStreptomycinSulfanilamideThioureaUreaseanti-microbialanti-ureaseSAR and molecular dockingsulphonamidesynthesisα-glucosidase

Identifiers

PMID36296720
PMCPMC9609496
OpenAlexW4307272925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.