Evidence map›Paper›PMID 36296679›Full record

ArticleMolecules (Basel, Switzerland)2022

Structural Prediction and Characterization of

Rodrigo Bainy Leal, Josiane Mann, Vanir Reis Pinto-Junior, Messias Vital Oliveira, Vinicius Jose Silva Osterne, Ingrid Alessandra Victoria Wolin, Ana Paula Machado Nascimento, Priscilla Gomes Welter, Valeria Maria Sousa Ferreira, Alice Araujo Silva and 3 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Rodrigo Bainy LealDepartamento de Bioquímica, Universidade Federal de Santa Catarina (UFSC), Florianópolis 88040-900, SC, Brazil.ORCID 0000-0003-2536-6888
Josiane MannDepartamento de Bioquímica, Universidade Federal de Santa Catarina (UFSC), Florianópolis 88040-900, SC, Brazil.ORCID 0000-0001-9617-5400
Vanir Reis Pinto-JuniorDepartamento de Física, Universidade Federal do Ceará (UFC), Fortaleza 60440-970, CE, Brazil.
Messias Vital OliveiraDepartamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará (UFC), Fortaleza 60440-970, CE, Brazil.
Vinicius Jose Silva OsterneDepartamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará (UFC), Fortaleza 60440-970, CE, Brazil.
Ingrid Alessandra Victoria WolinDepartamento de Bioquímica, Universidade Federal de Santa Catarina (UFSC), Florianópolis 88040-900, SC, Brazil.
Ana Paula Machado NascimentoDepartamento de Bioquímica, Universidade Federal de Santa Catarina (UFSC), Florianópolis 88040-900, SC, Brazil.
Priscilla Gomes WelterDepartamento de Bioquímica, Universidade Federal de Santa Catarina (UFSC), Florianópolis 88040-900, SC, Brazil.ORCID 0000-0002-0278-7746
Valeria Maria Sousa FerreiraDepartamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará (UFC), Fortaleza 60440-970, CE, Brazil.
Alice Araujo SilvaDepartamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará (UFC), Fortaleza 60440-970, CE, Brazil.
Rodrigo Lopes SeegerDepartamento de Bioquímica, Universidade Federal de Santa Catarina (UFSC), Florianópolis 88040-900, SC, Brazil.
Kyria Santiago NascimentoDepartamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará (UFC), Fortaleza 60440-970, CE, Brazil.
Benildo Sousa CavadaDepartamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará (UFC), Fortaleza 60440-970, CE, Brazil.ORCID 0000-0002-5791-6170
Universidade Federal do Ceará · BRUniversidade Federal de Santa Catarina · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A glioblastoma (GBM) is a highly malignant primary brain tumor with a poor prognosis because of its invasiveness and high resistance to current therapies. In GBMs, abnormal glycosylation patterns are associated with malignancy, which allows for the use of lectins as tools for recognition and therapy. More specifically, lectins can interact with glycan structures found on the malignant cell surface. In this context, the present work aimed to investigate the antiglioma potential of ConGF, a lectin purified from

Indexed as

CanavaliaFabaceaeAcridine OrangeCarbohydratesLectinsMatrix Metalloproteinase 1Plant LectinsPropidiumSeedsAcridine OrangeCarbohydratesLectinsMatrix Metalloproteinase 1Plant LectinsPropidiumCanavalia grandifloraglioblastomalectinmatrix metalloproteinase 1

Identifiers

PMID36296679
PMCPMC9612022
OpenAlexW4306937103

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.