Evidence map›Paper›PMID 36296666›Full record

ArticleMolecules (Basel, Switzerland)2022

(-)-Adaline from the

David P Richards, Rohit N Patel, Ian R Duce, Bhupinder P S Khambay, Michael A Birkett, John A Pickett, Ian R Mellor

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

David P RichardsSchool of Life Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Rohit N PatelSchool of Life Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK.ORCID 0000-0003-4070-3256
Ian R DuceSchool of Life Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Bhupinder P S KhambayProtecting Crops and the Environment, Rothamsted Research, West Common, Harpenden AL5 2JQ, UK.
Michael A BirkettProtecting Crops and the Environment, Rothamsted Research, West Common, Harpenden AL5 2JQ, UK.
John A PickettProtecting Crops and the Environment, Rothamsted Research, West Common, Harpenden AL5 2JQ, UK.ORCID 0000-0002-8386-3770
Ian R MellorSchool of Life Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK.ORCID 0000-0002-8332-5155
University of Nottingham · GBRothamsted Research · GB

Funding

Biotechnology and Biological Sciences Research Council DTP University of Nottingham-Rothamsted ResearchLawes Trust PhD Studentship
6 · The paper itself

Abstract

Ladybird beetles (Coleoptera: Coccinellidae) possess strong chemical defences that are secreted in response to stress and are also found on the coating of eggs, which are rich in alkaloids that are responsible for their toxicity to other species. Recent studies have shown that alkaloids from several species of ladybird beetle can target nicotinic acetylcholine receptors (nAChRs) acting as receptor antagonists. Here, we have explored the actions of (-)-adaline, found in the 2-spot (

Indexed as

AlkaloidsColeopteraReceptors, NicotinicAnimalsBridged-Ring CompoundsMammalsNicotinic AntagonistsPiperidinesRatsXenopus laevisadalineAlkaloidsBridged-Ring CompoundsNicotinic AntagonistsPiperidinesReceptors, NicotinicAdalia bipunctataAdalia decempunctata(−)-adalinenicotinic acetylcholine receptorpatch clampvoltage clamp

Identifiers

PMID36296666
PMCPMC9611057
OpenAlexW4306937267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.