Evidence map›Paper›PMID 36296639›Full record

ArticleMolecules (Basel, Switzerland)2022

Antibacterial Porous Systems Based on Polylactide Loaded with Amikacin.

Marta Glinka, Katerina Filatova, Justyna Kucińska-Lipka, Tomáš Šopík, Eva Domincová Bergerová, Veronika Mikulcová, Andrzej Wasik, Vladimir Sedlařík

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Marta GlinkaDepartment of Analytical Chemistry, Faculty of Chemistry, Gdańsk University of Technology, 11/12 G. Narutowicza Street, 80-233 Gdańsk, Poland.ORCID 0000-0003-4392-0344
Katerina FilatovaCentre of Polymer Systems, University Institute, Tomas Bata University in Zlín, Tomáše Bati 5678 Street, 760 01 Zlín, Czech Republic.
Justyna Kucińska-LipkaDepartment of Polymer Technology, Faculty of Chemistry, Gdańsk University of Technology, 11/12 G. Narutowicza Street, 80-233 Gdańsk, Poland.ORCID 0000-0001-8522-3198
Tomáš ŠopíkCentre of Polymer Systems, University Institute, Tomas Bata University in Zlín, Tomáše Bati 5678 Street, 760 01 Zlín, Czech Republic.ORCID 0000-0001-5671-1889
Eva Domincová BergerováCentre of Polymer Systems, University Institute, Tomas Bata University in Zlín, Tomáše Bati 5678 Street, 760 01 Zlín, Czech Republic.ORCID 0000-0002-7046-9782
Veronika MikulcováCentre of Polymer Systems, University Institute, Tomas Bata University in Zlín, Tomáše Bati 5678 Street, 760 01 Zlín, Czech Republic.
Andrzej WasikDepartment of Analytical Chemistry, Faculty of Chemistry, Gdańsk University of Technology, 11/12 G. Narutowicza Street, 80-233 Gdańsk, Poland.ORCID 0000-0002-1758-3893
Vladimir SedlaříkCentre of Polymer Systems, University Institute, Tomas Bata University in Zlín, Tomáše Bati 5678 Street, 760 01 Zlín, Czech Republic.
Tomas Bata University in Zlín · CZGdańsk University of Technology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three porous matrices based on poly(lactic acid) are proposed herein for the controlled release of amikacin. The materials were fabricated by the method of spraying a surface liquid. Description is given as to the possibility of employing a modifier, such as a silica nanocarrier, for prolonging the release of amikacin, in addition to using chitosan to improve the properties of the materials, e.g., stability and sorption capacity. Depending on their actual composition, the materials exhibited varied efficacy for drug loading, as follows: 25.4 ± 2.2 μg/mg (matrices with 0.05%

Indexed as

AmikacinChitosanAnti-Bacterial AgentsDelayed-Action PreparationsEscherichia coliMicrobial Sensitivity TestsPolyestersPorosityPseudomonas aeruginosaSilicon DioxideAmikacinAnti-Bacterial AgentsChitosanDelayed-Action PreparationsPolyesterspoly(lactide)Silicon Dioxideamikacindrug delivery systemspoly(lactic acid)porous matricestissue engineering

Identifiers

PMID36296639
PMCPMC9609933
OpenAlexW4306835848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.