Evidence map›Paper›PMID 36296633›Full record

ArticleMolecules (Basel, Switzerland)2022

Anti-HIV Ermiasolides from

Ermias Mergia Terefe, Faith Apolot Okalebo, Solomon Derese, Moses K Langat, Eduard Mas-Claret, Kamal Ahmad Qureshi, Mariusz Jaremko, Joseph Muriuki

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Journal of experimental pharmacology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ermias Mergia TerefeDepartment of Pharmacology and Pharmacognosy, School of Pharmacy and Health Sciences, United States International University-Africa, Nairobi P.O. Box 14634-00800, Kenya.ORCID 0000-0003-0630-8228
Faith Apolot OkaleboDepartment of Pharmacology and Pharmacognosy, College of Health Sciences, University of Nairobi, Nairobi P.O. Box 30197-00100, Kenya.
Solomon DereseDepartment of Chemistry, University of Nairobi, Nairobi P.O. Box 30197-00100, Kenya.ORCID 0000-0002-2640-3583
Moses K LangatRoyal Botanic Gardens, Kew, Kew Green, Richmond, Surrey TW9 3AE, UK.ORCID 0000-0001-8079-7774
Eduard Mas-ClaretRoyal Botanic Gardens, Kew, Kew Green, Richmond, Surrey TW9 3AE, UK.
Kamal Ahmad QureshiDepartment of Pharmaceutics, Unaizah College of Pharmacy, Qassim University, Unaizah 51911, Saudi Arabia.ORCID 0000-0002-3498-797X
Mariusz JaremkoSmart-Health Initiative (SHI) and Red Sea Research Center (RSRC), Division of Biological and Environmental Sciences and Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal 23955, Saudi Arabia.
Joseph MuriukiCentre for Virus Research, Kenya Medical Research Institute, Nairobi P.O. Box 14634-00800, Kenya.

Funding

United States International University-Africa Internal Grant No. 10-2854
6 · The paper itself

Abstract

In recent years, elucidation of novel anti-HIV bioactive compounds from natural products is gaining importance rapidly, not only from the research and publications, but also from controlled clinical studies. Here we report three new anti-HIV eudesmane-type sesquiterpenes, 5β-Hydroxy-8α-methoxy eudesm-7(11)-en-12,8-olide (

Indexed as

Biological ProductsCrotonSesquiterpenesSesquiterpenes, EudesmaneMolecular Docking SimulationMolecular StructurePeptide HydrolasesBiological ProductsPeptide HydrolasesSesquiterpenesSesquiterpenes, Eudesmaneanti-HIV activityCroton megalocarpuscytotoxicityermiasolidesHIV-1

Identifiers

PMID36296633
PMCPMC9610617

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.