ReviewMolecules (Basel, Switzerland)2022
The Hydrophobic Effects: Our Current Understanding.
Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed.
- Predicting Supramolecular Self-Assembly of Peptide Structures with AlphaFold3.bioRxiv : the preprint server for biology · 2026Article
- Liposomes, Niosomes, Ethosomes, and Transethosomes for Curcumin and Chlorogenic Acid Delivery: Formulation Design and Dermal Performance.Antioxidants (Basel, Switzerland) · 2026Review
- Integrated Phytochemical and Pharmacological Insights intoPlants (Basel, Switzerland) · 2026Review
- Silk-Fibroin-Based Adhesive Hydrogels: Mechanistic Insights and Biomedical ApplicationsA Review.ACS omega · 2026Review
- Design of strictly orthogonal biosensors for maximizing renewable biofuel overproduction.Journal of advanced research · 2026Article
- Temperature Tolerance of Self-Assembled Gels and Viscoelastic Solutions of Wormlike Micelles of Potassium Oleate Induced by Embedded Cellulose Nanocrystals.Gels (Basel, Switzerland) · 2026Article
- Enhanced Transmembrane Delivery of Chemotherapeutic Agent Doxorubicin by Carbon Nanotubes Under Plasma Synergy: Molecular Dynamics Insights.Biomolecules · 2026Article
- Leveraging Dynamic Electrostatic and Hydrophobic Interactions for Biomedical Hydrogels.ACS macro letters · 2026Review
- Aqueous OH Kinetics of Aliphatic Carboxylic Acids: New Data and Updated Structure-Activity Relationship.The journal of physical chemistry. A · 2026Article
- Dependence of Wenzel-Cassie Transition on Droplet Size: The Critical Water Droplet.Materials (Basel, Switzerland) · 2026Article
- A bioinspired microdevice unifying energy storage and actuation through hydration control.Nature communications · 2026Article
- Thermodynamic Data Remain a Hot Tip for Decoding Binding Affinity and Water Impact on Protein-Ligand Complex Formation to Assist Lead Optimization.Journal of medicinal chemistry · 2026Review
- Evaluation of molecular interactions of vaping juice components with ACE2 receptor.Scientific reports · 2026Article
- Mild One-Step Protein Recovery from Microalgae Cultivated in Swine Wastewater Using Natural Deep Eutectic Solvent-Based Aqueous Biphasic Systems.Molecules (Basel, Switzerland) · 2026Article
- Assessing Hydrolytic Activity of Surfactant-Based Nanozymes: Methodological and Kinetic Considerations.Nanomaterials (Basel, Switzerland) · 2026Review
- Methods for evaluating bacterial dispersal on hyphal networks.microLife · 2026Article
- TRAMbio: a flexible python package for graph rigidity analysis of macromolecules.BMC bioinformatics · 2025Article
- Ozone-Assisted Green Upgrading ofFoods (Basel, Switzerland) · 2025Article
- In-silico screening of small compounds against Lassa fever haemorrhagic virus nucleoprotein.Scientific reports · 2025Article
- Physics-Based Solubility Prediction for Organic Molecules.Chemical reviews · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hydrophobic interactions are involved in and believed to be the fundamental driving force of many chemical and biological phenomena in aqueous environments. This review focuses on our current understanding on hydrophobic effects. As a solute is embedded into water, the interface appears between solute and water, which mainly affects the structure of interfacial water (the topmost water layer at the solute/water interface). From our recent structural studies on water and air-water interface, hydration free energy is derived and utilized to investigate the origin of hydrophobic interactions. It is found that hydration free energy depends on the size of solute. With increasing the solute size, it is reasonably divided into initial and hydrophobic solvation processes, and various dissolved behaviors of the solutes are expected in different solvation processes, such as dispersed and accumulated distributions in solutions. Regarding the origin of hydrophobic effects, it is ascribed to the structural competition between the hydrogen bondings of interfacial and bulk water. This can be applied to understand the characteristics of hydrophobic interactions, such as the dependence of hydrophobic interactions on solute size (or concentrations), the directional natures of hydrophobic interactions, and temperature effects on hydrophobic interactions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.