Evidence map›Paper›PMID 36296585›Full record

ArticleMolecules (Basel, Switzerland)2022

Discovery of 2',6-Bis(4-hydroxybenzyl)-2-acetylcyclohexanone, a Novel FtsZ Inhibitor.

Hsuan-Yu J Lin, Rachana Rao Battaje, Jinlong Tan, Munikumar Doddareddy, Hemendra Pal Singh Dhaked, Shalini Srivastava, Bryson A Hawkins, Laith Mohammad Hilal Al-Shdifat, David E Hibbs, Dulal Panda and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Hsuan-Yu J LinSydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0003-2992-7793
Rachana Rao BattajeDepartment of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai 400076, India.
Jinlong TanSydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.
Munikumar DoddareddySydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.
Hemendra Pal Singh DhakedDepartment of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai 400076, India.
Shalini SrivastavaDepartment of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai 400076, India.
Bryson A HawkinsSydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-0280-039X
Laith Mohammad Hilal Al-ShdifatSydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-3953-0039
David E HibbsSydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.
Dulal PandaDepartment of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai 400076, India.
Paul W GroundwaterSydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-4932-2030
The University of Sydney · AUIndian Institute of Technology Bombay · IN

Funding

Department of Science and Technology CRG/2019/000566
6 · The paper itself

Abstract

Multi-drug resistance is increasing in the pathogenic bacterium

Indexed as

Bacterial ProteinsCytoskeletal ProteinsAlkaline PhosphataseAnti-Bacterial AgentsBacillus subtilisCyclohexanonesTubulin2-acetylcyclohexanoneAlkaline PhosphataseAnti-Bacterial AgentsBacterial ProteinsCyclohexanonesCytoskeletal ProteinsTubulincell divisionchemical synthesisFtsZ inhibitormolecular dockingZ-ring

Identifiers

PMID36296585
PMCPMC9610434
OpenAlexW4306764963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.