Evidence map›Paper›PMID 36296479›Full record

ReviewMolecules (Basel, Switzerland)2022

From Plant to Yeast-Advances in Biosynthesis of Artemisinin.

Le Zhao, Yunhao Zhu, Haoyu Jia, Yongguang Han, Xiaoke Zheng, Min Wang, Weisheng Feng

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. A Systematic Review of Alternative Artemisinin Production Strategies.International journal of molecular sciences · 2025
    Pooled it
  2. Article
  3. Article
  4. Characterization of high-artemisinin yieldingBiochemistry and biophysics reports · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Supercritical COBiotechnology notes (Amsterdam, Netherlands) · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Engineering a non-model yeastSynthetic and systems biotechnology · 2024
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Le ZhaoSchool of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.ORCID 0000-0002-1213-1126
Yunhao ZhuSchool of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Haoyu JiaSchool of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Yongguang HanSchool of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Xiaoke ZhengSchool of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Min WangCollege of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, China.
Weisheng FengSchool of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
First Affiliated Hospital of Henan University · CNBeijing Technology and Business University · CN

Funding

Henan Province High-Level Personnel Special Support "ZhongYuan One Thousand People Plan" ZYQR201810080Major Science and Technology Project in Henan Province 171100310500National Key Research and Development Project 2017YFC1702800, 2019YFC1708802Training Program for Young Teachers in Colleges and Universities of Henan Province 2021GGJS086
6 · The paper itself

Abstract

Malaria is a life-threatening disease. Artemisinin-based combination therapy (ACT) is the preferred choice for malaria treatment recommended by the World Health Organization. At present, the main source of artemisinin is extracted from

Indexed as

AntimalarialsArtemisia annuaArtemisininsMalariaEscherichia coliPlant ProteinsSaccharomyces cerevisiaeTranscription FactorsAntimalarialsArtemisininsPlant ProteinsTranscription FactorsArtemisia annuaartemisiningenetic engineeringsynthetic biologytranscription factor

Identifiers

PMID36296479
PMCPMC9609949
OpenAlexW4306399134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.