Evidence map›Paper›PMID 36296441›Full record

ReviewMolecules (Basel, Switzerland)2022

Development of Biotechnological Photosensitizers for Photodynamic Therapy: Cancer Research and Treatment-From Benchtop to Clinical Practice.

Mariza Aires-Fernandes, Ramon Botelho Costa, Stéphanie Rochetti do Amaral, Cassamo Ussemane Mussagy, Valéria C Santos-Ebinuma, Fernando Lucas Primo

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Advancements and emerging trends in photodynamic therapy: innovations in cancer treatment and beyond.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Review
  8. Preclinical Evaluation of an Integrin αBioconjugate chemistry · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Divulging the potency of naturally derived photosensitizers in green PDT: an inclusive review Of mechanisms, advantages, and future prospects.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Review
  14. Review
  15. Review
  16. Article
  17. Role of Dark States and Stokes Shift Simulations for Tetraphenylpyrazine Compared to Other Donor-Acceptor Photosensitizers.Chemphyschem : a European journal of chemical physics and physical chemistry · 2024
    Article
  18. Carbon Dots in Photodynamic/Photothermal Antimicrobial Therapy.Nanomaterials (Basel, Switzerland) · 2024
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Mariza Aires-FernandesDepartment of Bioprocess and Biotechnology Engineering, School of Pharmaceutical Sciences, São Paulo State University-UNESP, Araraquara 14800-903, São Paulo, Brazil.ORCID 0000-0003-0412-6439
Ramon Botelho CostaDepartment of Bioprocess and Biotechnology Engineering, School of Pharmaceutical Sciences, São Paulo State University-UNESP, Araraquara 14800-903, São Paulo, Brazil.
Stéphanie Rochetti do AmaralDepartment of Bioprocess and Biotechnology Engineering, School of Pharmaceutical Sciences, São Paulo State University-UNESP, Araraquara 14800-903, São Paulo, Brazil.ORCID 0000-0003-2844-2604
Cassamo Ussemane MussagyEscuela de Agronomía, Facultad de Ciencias Agronómicas y de los Alimentos, Pontificia Universidad Católica de Valparaíso, Quillota 2260000, Chile.ORCID 0000-0003-2907-5826
Valéria C Santos-EbinumaDepartment of Bioprocess and Biotechnology Engineering, School of Pharmaceutical Sciences, São Paulo State University-UNESP, Araraquara 14800-903, São Paulo, Brazil.ORCID 0000-0002-6666-6695
Fernando Lucas PrimoDepartment of Bioprocess and Biotechnology Engineering, School of Pharmaceutical Sciences, São Paulo State University-UNESP, Araraquara 14800-903, São Paulo, Brazil.ORCID 0000-0001-6293-4157
Universidade Estadual Paulista (Unesp) · BRPontificia Universidad Católica de Valparaíso · CL

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior Finance Code 001National Council for Scientific and Technological Development 404416/2021-7São Paulo Research Foundation 2020/09396-8
6 · The paper itself

Abstract

Photodynamic therapy (PDT) is a noninvasive therapeutic approach that has been applied in studies for the treatment of various diseases. In this context, PDT has been suggested as a new therapy or adjuvant therapy to traditional cancer therapy. The mode of action of PDT consists of the generation of singlet oxygen (¹O

Indexed as

NeoplasmsPhotochemotherapyHumansOxygenPhotosensitizing AgentsReactive Oxygen SpeciesSinglet OxygenOxygenPhotosensitizing AgentsReactive Oxygen SpeciesSinglet Oxygenbiotechnological photosensitizerscancer therapymalignant tumorsnanobiotechnologyphotodynamic therapy

Identifiers

PMID36296441
PMCPMC9609562
OpenAlexW4306153435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.