Evidence map›Paper›PMID 36296411›Full record

ArticleMolecules (Basel, Switzerland)2022

Preparation and Evaluation of [

Johan Hygum Dam, Niels Langkjær, Christina Baun, Birgitte Brinkmann Olsen, Aaraby Yoheswaran Nielsen, Helge Thisgaard

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Optimization of automated radiosynthesis method for [EJNMMI radiopharmacy and chemistry · 2026
    Article
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  3. Pathological validation ofScientific reports · 2025
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  4. Article
  5. Superior lesion detection withQuantitative imaging in medicine and surgery · 2025
    Article
  6. Article
  7. The clinical benefits of [BMC medical imaging · 2025
    Article
  8. Evaluation of [Molecular imaging and biology · 2025
    Article
  9. Role ofFrontiers in medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Johan Hygum DamDepartment of Nuclear Medicine, Odense University Hospital, Kløvervænget 47, DK-5000 Odense, Denmark.ORCID 0000-0001-6577-7011
Niels LangkjærDepartment of Nuclear Medicine, Odense University Hospital, Kløvervænget 47, DK-5000 Odense, Denmark.ORCID 0000-0002-8729-937X
Christina BaunDepartment of Nuclear Medicine, Odense University Hospital, Kløvervænget 47, DK-5000 Odense, Denmark.ORCID 0000-0002-5199-9200
Birgitte Brinkmann OlsenDepartment of Surgical Pathology, Zealand University Hospital, Sygehusvej 10, DK-4000 Roskilde, Denmark.ORCID 0000-0002-6130-0387
Aaraby Yoheswaran NielsenDepartment of Nuclear Medicine, Odense University Hospital, Kløvervænget 47, DK-5000 Odense, Denmark.ORCID 0000-0003-2199-2857
Helge ThisgaardDepartment of Nuclear Medicine, Odense University Hospital, Kløvervænget 47, DK-5000 Odense, Denmark.ORCID 0000-0001-9492-448X
Odense University Hospital · DKUniversity of Southern Denmark · DKZealand University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe somatostatin receptors 1-5 are overexpressed on neuroendocrine neoplasms and, as such, represent a favorable target for molecular imaging. This study investigates the potential of [

methodsDOTA- and NOTA-NOC were radiolabeled with gallium-68 and NOTA-NOC with [

resultsGallium-68 was incorporated into DOTA- and NOTA-NOC in yields and radiochemical purities greater than 96.5%. NOTA-NOC was radiolabeled with [

conclusionsThe high tumor uptake of all radioligands was observed. However, [

Indexed as

Gallium RadioisotopesNeuroendocrine TumorsAnimalsHeterocyclic Compounds, 1-RingMiceOctreotidePositron-Emission TomographyPositron Emission Tomography Computed TomographyRadiopharmaceuticalsReceptors, SomatostatinTissue Distribution1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid1,4,7-triazacyclononane-N,N',N''-triacetic acidGallium-68Gallium RadioisotopesHeterocyclic Compounds, 1-RingOctreotideRadiopharmaceuticalsReceptors, SomatostatinAlFF-18gallium-68neuroendocrineoctreotidePET

Identifiers

PMID36296411
PMCPMC9609173
OpenAlexW4304689123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.