Evidence map›Paper›PMID 36296389›Full record

ReviewMolecules (Basel, Switzerland)2022

Recent Synthetic Biology Approaches for Temperature- and Light-Controlled Gene Expression in Bacterial Hosts.

Jongdoo Choi, Jiyeun Ahn, Jieun Bae, Minseob Koh

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Temperature-Dependent Recombinase-Based Genetic Circuits.International journal of molecular sciences · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jongdoo ChoiDepartment of Chemistry, Pusan National University, Busan 46241, Korea.ORCID 0000-0001-8761-3843
Jiyeun AhnDepartment of Chemistry, Pusan National University, Busan 46241, Korea.
Jieun BaeDepartment of Chemistry, Pusan National University, Busan 46241, Korea.ORCID 0000-0002-5967-3934
Minseob KohDepartment of Chemistry, Pusan National University, Busan 46241, Korea.ORCID 0000-0003-1935-4776

Funding

National Research Foundation of Korea 2021R1A4A1021950Pusan National University Research Grant, 2020
6 · The paper itself

Abstract

The expression of genes of interest (GOI) can be initiated by providing external stimuli such as temperature shifts and light irradiation. The application of thermal or light stimuli triggers structural changes in stimuli-sensitive biomolecules within the cell, thereby inducing or repressing gene expression. Over the past two decades, several groups have reported genetic circuits that use natural or engineered stimuli-sensitive modules to manipulate gene expression. Here, we summarize versatile strategies of thermosensors and light-driven systems for the conditional expression of GOI in bacterial hosts.

Indexed as

Gene Regulatory NetworksSynthetic BiologyGene ExpressionTemperaturegenetic code expansionoptogeneticsphotocaged inducerphotoswitchthermosensor

Identifiers

PMID36296389
PMCPMC9611254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.