Evidence map›Paper›PMID 36295973›Full record

ArticleMicromachines2022

A Self-Regulated Microfluidic Device with Thermal Bubble Micropumps.

Gang Guo, Xuanye Wu, Demeng Liu, Lingni Liao, Di Zhang, Yi Zhang, Tianjiao Mao, Yuhan He, Peng Huang, Wei Wang and 6 more

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Gang GuoDepartment of Microelectronics, Shanghai University, Shanghai 200000, China.
Xuanye WuDepartment of Microelectronics, Shanghai University, Shanghai 200000, China.
Demeng LiuDepartment of Microelectronics, Shanghai University, Shanghai 200000, China.
Lingni LiaoShanghai Industrial μTechnology Research Institute, Shanghai 200000, China.
Di ZhangShanghai Industrial μTechnology Research Institute, Shanghai 200000, China.
Yi ZhangShanghai Industrial μTechnology Research Institute, Shanghai 200000, China.
Tianjiao MaoShanghai Industrial μTechnology Research Institute, Shanghai 200000, China.
Yuhan HeShanghai Industrial μTechnology Research Institute, Shanghai 200000, China.
Peng HuangShanghai Industrial μTechnology Research Institute, Shanghai 200000, China.
Wei WangShanghai Aure Technology limited Company, Shanghai 200000, China.
Lin SuShanghai Aure Technology limited Company, Shanghai 200000, China.
Shuhua WangShanghai Aure Technology limited Company, Shanghai 200000, China.
Qi LiuShanghai Industrial μTechnology Research Institute, Shanghai 200000, China.
Xingfeng MaDepartment of Microelectronics, Shanghai University, Shanghai 200000, China.
Nan ShiShanghai Industrial μTechnology Research Institute, Shanghai 200000, China.
Yimin GuanDepartment of Microelectronics, Shanghai University, Shanghai 200000, China.
Shanghai Industrial Technology Institute · CNShanghai University · CN

Funding

Key Project of National Natural Science Foundation of the People's Republic of China 82130069Ministry of Industry and Information Technology of the People's Republic of China CEIEC-2021-ZM02-0188Ministry of Science and Technology of the People's Republic of China 2018ZX01031-301
6 · The paper itself

Abstract

Currently, many microchips must rely on an external force (such as syringe pump, electro-hydrodynamic pump, and peristaltic pump, etc.) to control the solution in the microchannels, which probably adds manual operating errors, affects the accuracy of fluid manipulation, and enlarges the noise of signal. In addition, the reasonable integration of micropump and microchip remain the stumbling block for the commercialization of microfluidic technique. To solve those two problems, we designed and fabricated a thermal bubble micropump based on MEMS (micro-electro-mechanical systems) technique. Many parameters (voltage, pulse time, cycle delay time, etc.) affecting the performance of this micropump were explored in this work. The experimental results showed the flow rate of solution with the assistance of a micropump reached more than 15 μL/min in the optimal condition. Finally, a method about measuring total aflatoxin in Chinese herbs was successfully developed based on the integrated platform contained competitive immunoassay and our micropump-based microfluidics. Additionally, the limit of detection in quantifying total aflatoxin (AF) was 0.0615 pg/mL in this platform. The data indicate this combined technique of biochemical assays and micropump based microchip have huge potential in automatically, rapidly, and sensitively measuring other low concentration of biochemical samples with small volume.

Indexed as

aflatoxincompetitive immunoassaymicrofluidicsthermal bubble micropump

Identifiers

PMID36295973
PMCPMC9612009
OpenAlexW4297521789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.