Evidence map›Paper›PMID 36295665›Full record

ArticleMembranes2022

Modulation of Membrane Microviscosity by Protein-Mediated Carotenoid Delivery as Revealed by Time-Resolved Fluorescence Anisotropy.

Alexey N Semenov, Danil A Gvozdev, Dmitry V Zlenko, Elena A Protasova, Anastasia R Khashimova, Evgenia Yu Parshina, Adil A Baizhumanov, Natalia Yu Lotosh, Eleonora E Kim, Yuriy N Kononevich and 5 more

Open access · goldAbstract read
In one paragraph

Article in Membranes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Alexey N SemenovFaculty of Biology, M.V. Lomonosov Moscow State University, 1-12 Leninskie Gory St., Moscow 119991, Russia.ORCID 0000-0003-2324-7666
Danil A GvozdevFaculty of Biology, M.V. Lomonosov Moscow State University, 1-12 Leninskie Gory St., Moscow 119991, Russia.
Dmitry V ZlenkoFaculty of Biology, M.V. Lomonosov Moscow State University, 1-12 Leninskie Gory St., Moscow 119991, Russia.ORCID 0000-0002-4126-3080
Elena A ProtasovaFaculty of Biology, M.V. Lomonosov Moscow State University, 1-12 Leninskie Gory St., Moscow 119991, Russia.
Anastasia R KhashimovaFaculty of Biology, M.V. Lomonosov Moscow State University, 1-12 Leninskie Gory St., Moscow 119991, Russia.
Evgenia Yu ParshinaFaculty of Biology, M.V. Lomonosov Moscow State University, 1-12 Leninskie Gory St., Moscow 119991, Russia.ORCID 0000-0001-7072-0693
Adil A BaizhumanovFaculty of Biology, M.V. Lomonosov Moscow State University, 1-12 Leninskie Gory St., Moscow 119991, Russia.ORCID 0000-0001-9737-4516
Natalia Yu LotoshNational Research Center "Kurchatov Institute", 1 Acad. Kurchatov Sq., Moscow 123182, Russia.
Eleonora E KimA.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Moscow 119991, Russia.ORCID 0000-0003-3795-9947
Yuriy N KononevichA.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Moscow 119991, Russia.ORCID 0000-0003-3256-7995
Alexey A PakhomovA.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Moscow 119991, Russia.ORCID 0000-0001-7757-6452
Alla A SelishchevaFaculty of Biology, M.V. Lomonosov Moscow State University, 1-12 Leninskie Gory St., Moscow 119991, Russia.
Nikolai N SluchankoFederal Research Center of Biotechnology, Russian Academy of Sciences, 33 Leninsky Prospect, Moscow 119071, Russia.ORCID 0000-0002-8608-1416
Evgeny A ShirshinFaculty of Physics, M.V. Lomonosov Moscow State University, 1-2 Leninskie Gory St., Moscow 119991, Russia.
Eugene G MaksimovFaculty of Biology, M.V. Lomonosov Moscow State University, 1-12 Leninskie Gory St., Moscow 119991, Russia.ORCID 0000-0001-6767-1501
Lomonosov Moscow State University · RUA. N. Nesmeyanov Institute of Organoelement Compounds · RUKurchatov Institute · RURussian Academy of Sciences · RUSechenov University · RU

Funding

Kurchatov Institute Thematic plan of NRC "Kurchatov Institute" 1.8 "Investigation of energy generation and transmis-sion in the living organisms"Russian Foundation for Basic Research 20-54-12018Russian Science Foundation 22-25-00183
6 · The paper itself

Abstract

Carotenoids are potent antioxidants with a wide range of biomedical applications. However, their delivery into human cells is challenging and relatively inefficient. While the use of natural water-soluble carotenoproteins capable to reversibly bind carotenoids and transfer them into membranes is promising, the quantitative estimation of the delivery remains unclear. In the present work, we studied echinenone (ECN) delivery by cyanobacterial carotenoprotein AnaCTDH (C-terminal domain homolog of the Orange Carotenoid Protein from

Indexed as

carotenoid deliverycarotenoproteinsFRETmembrane microviscositymolecular dynamicstime-resolved fluorescence anisotropy

Identifiers

PMID36295665
PMCPMC9609150
OpenAlexW4296746225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.