Evidence map›Paper›PMID 36295627›Full record

ReviewMedicina (Kaunas, Lithuania)2022

Use of Ultra-Widefield Fluorescein Angiography to Guide the Treatment to Idiopathic Retinal Vasculitis, Aneurysms, and Neuroretinitis-Case Report and Literature Review.

Ping-Ping Meng, Chun-Ju Lin, Ning-Yi Hsia, Chun-Ting Lai, Henry Bair, Jane-Ming Lin, Wen-Lu Chen, Yi-Yu Tsai

Open access · goldAbstract readReviewCase Reports
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Ping-Ping MengDepartment of Ophthalmology, China Medical University Hospital, China Medical University, Taichung City 404, Taiwan.
Chun-Ju LinDepartment of Ophthalmology, China Medical University Hospital, China Medical University, Taichung City 404, Taiwan.ORCID 0000-0002-7880-9198
Ning-Yi HsiaDepartment of Ophthalmology, China Medical University Hospital, China Medical University, Taichung City 404, Taiwan.ORCID 0000-0002-9398-1316
Chun-Ting LaiDepartment of Ophthalmology, China Medical University Hospital, China Medical University, Taichung City 404, Taiwan.
Henry BairDepartment of Ophthalmology, China Medical University Hospital, China Medical University, Taichung City 404, Taiwan.
Jane-Ming LinDepartment of Ophthalmology, China Medical University Hospital, China Medical University, Taichung City 404, Taiwan.
Wen-Lu ChenDepartment of Ophthalmology, China Medical University Hospital, China Medical University, Taichung City 404, Taiwan.
Yi-Yu TsaiDepartment of Ophthalmology, China Medical University Hospital, China Medical University, Taichung City 404, Taiwan.
China Medical University · TWAsia University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo review the clinical features, diagnosis, and treatment of idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) and to report a case with the use of ultra-widefield fluorescein angiography (UWFA) for confirming the precise staging of IRVAN and aid in early treatment. The patient improved after being treated with intravitreal aflibercept injection.

resultsA 26-year-old female complained of progressive blurred vision OD for one week. Her BCVA was 0.6 OD and 1.0 OS. Fundus examination showed vitritis, retinal hemorrhage, and vasculitis over bilateral eyes. Fluorescein angiography (FA) with a 55 degree of view revealed aneurysmal dilations of the peripapillary arteriole, peripapillary focal leakage, venous leakage, and capillary nonperfusion area. Stage 2 IRVAN was impressed OU. Oral prednisolone was administered. After four months, she experienced decreased visual acuity OS. Optical coherence tomography (OCT) revealed subretinal and intraretinal fluid with hyperreflective material. One posterior subtenon triamcinolone and one intravitreal aflibercept injection were performed OS, and macular edema subsided. A 105-degree ultra-widefield fluorescein angiography (UWFA) showed multiple peripheral background hypofluorescence areas corresponding to capillary nonperfusion. Retinal neovascularization (NV) was found OS, which had not been revealed by the previous 55-degree FA. Stage 3 IRVAN was made OS and panretinal laser photocoagulation (PRP) was performed. Oral prednisone and cyclosporine were prescribed. Her vision improved to 1.0 OU.

conclusionUWFA provides visualization of peripheral retinal pathology and for precise staging. It also had direct implications in the follow-up and treatment strategy.

Indexed as

AneurysmCyclosporinsRetinal VasculitisRetinitisAdultFemaleFluorescein AngiographyHumansPrednisolonePrednisoneRetinal VesselsTomography, Optical CoherenceCyclosporinsPrednisolonePrednisoneaneurysms and neuroretinitiscase reportidiopathic retinal vasculitispanretinal laser photocoagulationultra-widefield fluorescein angiography

Identifiers

PMID36295627
PMCPMC9611749
OpenAlexW4306391254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.