Evidence map›Paper›PMID 36295515›Full record

ArticleMedicina (Kaunas, Lithuania)2022

Aseptic Abscess Syndrome in Rheumatoid Arthritis Patient.

Agnieszka Owczarczyk-Saczonek, Marta Kasprowicz-Furmańczyk, Jakub Kuna, Paulina Klimek, Magdalena Krajewska-Włodarczyk

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. [Diagnostics and treatment of splenic abscesses].Chirurgie (Heidelberg, Germany) · 2023
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Agnieszka Owczarczyk-SaczonekDepartment of Dermatology, Sexually Transmitted Diseases and Clinical Immunology, School of Medicine, Collegium Medicum, The University of Warmia and Mazury, Al. Wojska Polskiego 30, 10-229 Olsztyn, Poland.ORCID 0000-0002-8372-0438
Marta Kasprowicz-FurmańczykDepartment of Dermatology, Sexually Transmitted Diseases and Clinical Immunology, School of Medicine, Collegium Medicum, The University of Warmia and Mazury, Al. Wojska Polskiego 30, 10-229 Olsztyn, Poland.ORCID 0000-0002-4177-8404
Jakub KunaDepartment of Rheumatology, School of Medicine, Collegium Medicum, University of Warmia and Mazury, 10-900 Olsztyn, Poland.ORCID 0000-0002-4216-9731
Paulina KlimekDepartment of Dermatology, Sexually Transmitted Diseases and Clinical Immunology, School of Medicine, Collegium Medicum, The University of Warmia and Mazury, Al. Wojska Polskiego 30, 10-229 Olsztyn, Poland.
Magdalena Krajewska-WłodarczykDepartment of Rheumatology, School of Medicine, Collegium Medicum, University of Warmia and Mazury, 10-900 Olsztyn, Poland.ORCID 0000-0002-7857-347X
University of Warmia and Mazury in Olsztyn · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aseptic abscess syndrome (AAS) is a rare, potentially life-threatening disorder, with numerous features of neutrophilic dermatoses. The main symptoms include aseptic abscess-like collections in internal organs (spleen, liver, lungs), lack of microbes (bacteria, viruses, or parasites) after an exhaustive search, ineffectiveness of antibiotics, and high sensitivity to corticosteroid therapy. AAS is characterized by the development of deep, inflammatory abscesses and systemic symptoms (weight loss, abdominal pain, fever, and leukocytosis). They may be associated with inflammatory bowel disease (IBD) and autoimmune diseases. The patient in this study is a 67-year-old man, suffering from rheumatoid arthritis (RA), with numerous purulent abscesses in the mediastinum, within the subcutaneous tissue above the extension surfaces of the joints, and on the dorsum of the hands. The lesions are accompanied by bone destruction. The patient was treated with prednisone 40 mg and adalimumab, which resulted in a quick reduction of inflammatory markers and clinical improvement, as well as the healing and absorption of abscesses. Despite COVID-19 infection, treatment with remdesivir, prednisone, and adalimumab was continued, with the complete resolution of the lesions. AAS is difficult to recognize, so practitioners have to be aware of this condition, especially in patients with RA.

Indexed as

Arthritis, RheumatoidCOVID-19AbscessAdalimumabAdrenal Cortex HormonesAgedAnti-Bacterial AgentsHumansMalePrednisoneSyndromeAdalimumabAdrenal Cortex HormonesAnti-Bacterial AgentsPrednisoneadalimumabaseptic abscess syndromerheumatoid arthritis

Identifiers

PMID36295515
PMCPMC9609381
OpenAlexW4297542453

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.