Evidence map›Paper›PMID 36295241›Full record

ArticleMaterials (Basel, Switzerland)2022

Laser-Deposited Beta Type Ti-42Nb Alloy with Anisotropic Mechanical Properties for Pioneering Biomedical Implants with a Very Low Elastic Modulus.

Felipe Arias-González, Alejandra Rodríguez-Contreras, Miquel Punset, José María Manero, Óscar Barro, Mónica Fernández-Arias, Fernando Lusquiños, Javier Gil, Juan Pou

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Anisotropy of Additively Manufactured Metallic Materials.Materials (Basel, Switzerland) · 2024
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Felipe Arias-GonzálezLaserOn Research Group, CINTECX, School of Engineering, Universidade de Vigo (UVIGO), Lagoas Marcosende, 36310 Vigo, Spain.ORCID 0000-0002-0201-9624
Alejandra Rodríguez-ContrerasBiomaterials, Biomechanics and Tissue Engineering Group, Materials Science and Engineering Department, and Research Center for Biomedical Engineering, Universitat Politècnica de Catalunya (UPC), 08019 Barcelona, Spain.
Miquel PunsetBiomaterials, Biomechanics and Tissue Engineering Group, Materials Science and Engineering Department, and Research Center for Biomedical Engineering, Universitat Politècnica de Catalunya (UPC), 08019 Barcelona, Spain.ORCID 0000-0002-1904-8667
José María ManeroBiomaterials, Biomechanics and Tissue Engineering Group, Materials Science and Engineering Department, and Research Center for Biomedical Engineering, Universitat Politècnica de Catalunya (UPC), 08019 Barcelona, Spain.
Óscar BarroLaserOn Research Group, CINTECX, School of Engineering, Universidade de Vigo (UVIGO), Lagoas Marcosende, 36310 Vigo, Spain.ORCID 0000-0002-5466-3382
Mónica Fernández-AriasLaserOn Research Group, CINTECX, School of Engineering, Universidade de Vigo (UVIGO), Lagoas Marcosende, 36310 Vigo, Spain.ORCID 0000-0002-4157-8269
Fernando LusquiñosLaserOn Research Group, CINTECX, School of Engineering, Universidade de Vigo (UVIGO), Lagoas Marcosende, 36310 Vigo, Spain.
Javier GilSchool of Dentistry, Universitat Internacional de Catalunya (UIC), 08195 Sant Cugat del Vallès, Spain.ORCID 0000-0002-6824-1412
Juan PouLaserOn Research Group, CINTECX, School of Engineering, Universidade de Vigo (UVIGO), Lagoas Marcosende, 36310 Vigo, Spain.ORCID 0000-0002-8848-5617
Institut de Recerca Sant Joan de DéuUniversidade de Vigo · ESGalicia Sur Biomedical Foundation · ESUniversitat Internacional de Catalunya · ES

Funding

European Union MINECO-FEDER, EUGeneralitat de Catalunya 2017 SGR-1165SOADCO S.L. (Escaldes Engordany, Andorra) contractSpanish Government RTI2018-098075-B-C21Xunta de Galicia ED431C 2019/2Xunta de Galicia ED481B-2021-113
6 · The paper itself

Abstract

Present commercial titanium alloy implants have an elastic modulus higher than 100 GPa, whereas that of the cortical bone is much smaller (17−28 GPa). This elastic modulus mismatch produces a stress shielding effect and the resorption of the bone surrounding the implant. In the present work, a <100> fiber texture is developed in β type Ti-42Nb (wt%) alloy ingots generated by laser-directed energy deposition (LDED) in order to achieve anisotropic mechanical properties. In addition, we demonstrate that laser-deposited β type Ti-42Nb alloy ingots with an intense <100> fiber texture exhibit a very low elastic modulus in the building direction (Ez < 50 GPa) and high yield (σ0.2z > 700 MPa) and tensile (UTSz > 700 MPa) strengths. Laser-deposited Ti-42Nb alloy enhances the osteoinductive effect, promoting the adhesion, proliferation, and spreading of human osteoblast-like cells. Hence, we propose that laser-deposited β type Ti-42Nb alloy is a potentially promising candidate for the manufacturing of pioneering biomedical implants with a very low elastic modulus that can suppress stress shielding.

Indexed as

crystallographic texturecytocompatibilitylaser-directed energy depositionmicrostructuretitanium alloysYoung’s modulus

Identifiers

PMID36295241
PMCPMC9607472
OpenAlexW4306392276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.