Evidence map›Paper›PMID 36295083›Full record

ArticleLife (Basel, Switzerland)2022

MiR-134-5p/

Dongrong Liu, Yan Liu, Yun Hu, Ye Ming, Xuehuan Meng, Hao Tan, Leilei Zheng

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Dongrong LiuThe Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing 401147, China.
Yan LiuThe Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing 401147, China.
Yun HuThe Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing 401147, China.
Ye MingThe Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing 401147, China.
Xuehuan MengThe Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing 401147, China.
Hao TanThe Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing 401147, China.
Leilei ZhengThe Affiliated Stomatology Hospital, Chongqing Medical University, Chongqing 401147, China.
Stomatological Hospital of Chongqing Medical University · CNChongqing Medical University · CNFirst Affiliated Hospital of Chongqing Medical University · CNStomatology Hospital · CN

Funding

Medical Scientific Research Project of Chongqing cstc2020jcyj-msxmX0307, 2018ZDXM020National Natural Science Foundation of China 81470772
6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) are critical in regenerating tissues because they can differentiate into various tissue cells. MSCs interact closely with cells in the tissue microenvironment during the repair of damaged tissue. Although regarded as non-healing wounds, tumors can be treated by MSCs, which showed satisfactory treatment outcomes in previous reports. However, it is largely unknown whether the biological behaviors of MSCs would be affected by the tumor microenvironment. Exploring the truth of tumor microenvironmental cues driving MSCs tumor "wound" regeneration would provide a deeper understanding of the biological behavior of MSCs. Therefore, we mimicked the tumor microenvironment using co-cultured glioma C6 cells and rat MSCs, aiming to assess the proliferation and migration of MSCs and the associated effects of

Indexed as

migrationmiR-134-5pMSCsproliferationPvt1Stat3

Identifiers

PMID36295083
PMCPMC9604557
OpenAlexW4306951903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.