Evidence map›Paper›PMID 36295082›Full record

ArticleLife (Basel, Switzerland)2022

Guanidine Derivatives of Quinazoline-2,4(1

Alexander Spasov, Alexander Ozerov, Vadim Kosolapov, Natalia Gurova, Aida Kucheryavenko, Ludmila Naumenko, Denis Babkov, Viktor Sirotenko, Alena Taran, Alexander Borisov and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Alexander SpasovDepartment of Pharmacology & Bioinformatics, Volgograd State Medical University, 400001 Volgograd, Russia.ORCID 0000-0002-7185-4826
Alexander OzerovScientific Center for Innovative Drugs, Volgograd State Medical University, 400087 Volgograd, Russia.ORCID 0000-0002-4721-0959
Vadim KosolapovDepartment of Pharmacology & Bioinformatics, Volgograd State Medical University, 400001 Volgograd, Russia.ORCID 0000-0002-6702-1207
Natalia GurovaDepartment of Pharmacology & Bioinformatics, Volgograd State Medical University, 400001 Volgograd, Russia.
Aida KucheryavenkoDepartment of Pharmacology & Bioinformatics, Volgograd State Medical University, 400001 Volgograd, Russia.
Ludmila NaumenkoDepartment of Pharmacology & Bioinformatics, Volgograd State Medical University, 400001 Volgograd, Russia.
Denis BabkovDepartment of Pharmacology & Bioinformatics, Volgograd State Medical University, 400001 Volgograd, Russia.ORCID 0000-0002-9645-3324
Viktor SirotenkoDepartment of Pharmacology & Bioinformatics, Volgograd State Medical University, 400001 Volgograd, Russia.
Alena TaranDepartment of Pharmacology & Bioinformatics, Volgograd State Medical University, 400001 Volgograd, Russia.
Alexander BorisovScientific Center for Innovative Drugs, Volgograd State Medical University, 400087 Volgograd, Russia.
Elena SokolovaDepartment of Pharmacology & Bioinformatics, Volgograd State Medical University, 400001 Volgograd, Russia.
Vladlen KlochkovDepartment of Pharmacology & Bioinformatics, Volgograd State Medical University, 400001 Volgograd, Russia.
Darya MerezhkinaDepartment of Pharmaceutical & Toxicological Chemistry, Volgograd State Medical University, 400001 Volgograd, Russia.ORCID 0000-0002-9848-7149
Mikhail MiroshnikovDepartment of Pharmacology & Bioinformatics, Volgograd State Medical University, 400001 Volgograd, Russia.
Nadezhda OvsyankinaDepartment of Pharmacology & Bioinformatics, Volgograd State Medical University, 400001 Volgograd, Russia.
Alexey SmirnovDepartment of Pathological Anatomy, Volgograd State Medical University, 400131 Volgograd, Russia.
Yulia VelikorodnayaDepartment of Pathological Anatomy, Volgograd State Medical University, 400131 Volgograd, Russia.
Volgograd State Medical University · RU

Funding

Ministry of Science and Higher Education of the Russian Federation 075-15-2020-777
6 · The paper itself

Abstract

Quinazolines are a rich source of bioactive compounds. Previously, we showed NHE-1 inhibitory, anti-inflammatory, antiplatelet, intraocular pressure lowering, and antiglycating activity for a series of quinazoline-2,4(1

Indexed as

cytokine releaseLPSlung injurymacrophageNHE-1quinazoline-2,4(1H,3H)-dione

Identifiers

PMID36295082
PMCPMC9605072
OpenAlexW4306937828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.