Evidence map›Paper›PMID 36294939›Full record

ArticleLife (Basel, Switzerland)2022

Effect of a Proton Pump Inhibitor on the Duodenum Microbiome of Gastric Ulcer Patients.

Jung-Hyun Lim, Jongbeom Shin, Jin-Seok Park

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Role of the Small Intestinal Microbiota in Gastrointestinal Disorders.The Korean journal of helicobacter and upper gastrointestinal research · 2024
    Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jung-Hyun LimDigestive Disease Center, Department of Internal Medicine, Inha University School of Medicine, Incheon 22332, Korea.ORCID 0000-0003-3596-9420
Jongbeom ShinDigestive Disease Center, Department of Internal Medicine, Inha University School of Medicine, Incheon 22332, Korea.
Jin-Seok ParkDigestive Disease Center, Department of Internal Medicine, Inha University School of Medicine, Incheon 22332, Korea.

Funding

National Research Foundation of Korea NRF-202R1F1A1067621
6 · The paper itself

Abstract

The gut microbiota are regarded as a functional organ that plays a substantial role in human health and disease. Proton pump inhibitors (PPIs) are widely used in medicine but can induce changes in the overall gut microbiome and cause disease-associated dysbiosis. The microbiome of the duodenum has not been sufficiently studied, and the effects of PPIs on the duodenal microbiome are poorly understood. In this study, we investigated the effect of PPI administration on duodenum microbiota in patients with a gastric ulcer. A total of 12 gastric ulcer patients were included, and PPI (Ilaprazole, Noltec

Indexed as

biopsyduodenummicrobiotaPPI

Identifiers

PMID36294939
PMCPMC9605190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.