Evidence map›Paper›PMID 36294853›Full record

ArticleJournal of personalized medicine2022

Treatment Results of Endoscopic Transnasal Orbital Decompression for Graves' Orbitopathy-A Single-Center Retrospective Analysis in 28 Orbits of 16 Patients.

Krzysztof B Poślednik, Katarzyna Czerwaty, Nils Ludwig, Marta Molińska-Glura, Anna Jabłońska-Pawlak, Piotr Miśkiewicz, Ireneusz Kantor, Karolina Dżaman, Anna M Cyran, Mirosław J Szczepański

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Dysthyroid optic neuropathy: emerging treatment strategies.Journal of endocrinological investigation · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Krzysztof B PoślednikDepartment of Otolaryngology, Centre of Postgraduate Medical Education, 01-813 Warsaw, Poland.ORCID 0000-0003-2538-7064
Katarzyna CzerwatyDepartment of Otolaryngology, Centre of Postgraduate Medical Education, 01-813 Warsaw, Poland.ORCID 0000-0003-1311-8377
Nils LudwigDepartment of Oral and Maxillofacial Surgery, University Hospital Regensburg, 93053 Regensburg, Germany.ORCID 0000-0001-5561-2184
Marta Molińska-GluraDepartment of Economics and Forest Technology, Faculty of Forestry and Wood Technology, Poznan University of Life Sciences, 60-624 Poznan, Poland.
Anna Jabłońska-PawlakDepartment of Ophthalmology, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0002-6118-6705
Piotr MiśkiewiczDepartment of Internal Medicine and Endocrinology, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0002-9024-9015
Ireneusz KantorDepartment of Otolaryngology, Centre of Postgraduate Medical Education, 01-813 Warsaw, Poland.
Karolina DżamanDepartment of Otolaryngology, Centre of Postgraduate Medical Education, 01-813 Warsaw, Poland.ORCID 0000-0003-4211-7664
Anna M CyranLegorreta Cancer Center, Department of Pathology and Laboratory Medicine, Brown University, Providence, RI 02912, USA.
Mirosław J SzczepańskiDepartment of Otolaryngology, Centre of Postgraduate Medical Education, 01-813 Warsaw, Poland.ORCID 0000-0002-5206-137X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graves’ orbitopathy (GO) is an extrathyroidal manifestation of Graves’ disease (GD), which can be associated with corneal ulcerations or optic neuropathy in severe forms. Transnasal endoscopic orbital decompression (TEOD) is a surgical procedure performed in order to decrease the intraorbital pressure by removing part of its bony borders in cases with excessive mass in orbit. The aim of this study was to present the results and evaluate the efficacy of TEOD for GO. The retrospective study included 28 orbits (16 patients) who underwent TEOD from 2017 to 2020. Outcome was evaluated based on visual acuity improvement, clinical activity score (CAS) decrease, proptosis, and intraocular pressure (IOP) reduction. A preoperative best-corrected visual acuity (BCVA) increased from 0.69 ± 0.385 (mean ± standard deviation) to 0.74 ± 0.332 (p = 0.17) postoperatively. CAS decreased in 15 orbits postoperatively. Proptosis decreased from 22.89 ± 1.873 mm to 21.25 ± 2.053 mm (p < 0.05). IOP decreased from a preoperative 16.11 ± 3.93 mmHg to 14.40 ± 3.27 mmHg (p < 0.05) postoperatively. In addition, postoperative relief of exposure keratitis was observed. The analysis of development of iatrogenic diplopia revealed increasing in degree of diplopia. TEOD shows rare complications, but significant improvements in BCVA, CAS, proptosis, and IOP.

Indexed as

compressive optic neuropathydysthyroid optic neuropathyendoscopic transnasal orbital decompressionGraves’ orbitopathy

Identifiers

PMID36294853
PMCPMC9605419

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.