Evidence map›Paper›PMID 36294557›Full record

ArticleJournal of fungi (Basel, Switzerland)2022

Caspofungin Affects Extracellular Vesicle Production and Cargo in

Rafaela F Amatuzzi, Daniel Zamith-Miranda, Isadora F Munhoz da Rocha, Aline C R Lucena, Sharon de Toledo Martins, Rodrigo Streit, Charley C Staats, Gabriel Trentin, Fausto Almeida, Marcio L Rodrigues and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 17 citations in OpenAlex.

  1. Antifungal turbinmicin alters functional vesicle cargo.Antimicrobial agents and chemotherapy · 2026
    Article
  2. Transfer RNA Fragments in Diseases of Sensory Organs.International journal of molecular sciences · 2026
    Review
  3. Review
  4. Caspofungin Reshapes the Extracellular Vesicles Metabolome ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  5. Functional properties ofMicrobiology (Reading, England) · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Stress Conditions Affect the Immunomodulatory Potential ofInternational journal of molecular sciences · 2023
    Article
  14. Review
  15. Extracellular Vesicles fromJournal of fungi (Basel, Switzerland) · 2023
    Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Rafaela F AmatuzziGene Expression Regulation Laboratory, Carlos Chagas Institute, FIOCRUZ PR, Curitiba 81350-010, Brazil.ORCID 0000-0002-8743-1625
Daniel Zamith-MirandaDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0000-0001-7532-2432
Isadora F Munhoz da RochaGene Expression Regulation Laboratory, Carlos Chagas Institute, FIOCRUZ PR, Curitiba 81350-010, Brazil.
Aline C R LucenaLaboratory for Applied Sciences and Technology in Health, Carlos Chagas Institute, FIOCRUZ PR, Curitiba 81350-010, Brazil.
Sharon de Toledo MartinsGene Expression Regulation Laboratory, Carlos Chagas Institute, FIOCRUZ PR, Curitiba 81350-010, Brazil.ORCID 0000-0003-2046-4809
Rodrigo StreitPrograma de Pós-Graduação em Biologia Celular e Molecular, Centro de Biotecnologia, Universidade Federal do Rio Grande do Sul, Porto Alegre 91509-900, Brazil.
Charley C StaatsPrograma de Pós-Graduação em Biologia Celular e Molecular, Centro de Biotecnologia, Universidade Federal do Rio Grande do Sul, Porto Alegre 91509-900, Brazil.ORCID 0000-0002-2433-6903
Gabriel TrentinDepartment of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirao Preto 14040-900, Brazil.ORCID 0000-0003-2240-8819
Fausto AlmeidaDepartment of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirao Preto 14040-900, Brazil.
Marcio L RodriguesGene Expression Regulation Laboratory, Carlos Chagas Institute, FIOCRUZ PR, Curitiba 81350-010, Brazil.ORCID 0000-0002-6081-3439
Joshua D NosanchukDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0000-0001-9905-5754
Lysangela R AlvesGene Expression Regulation Laboratory, Carlos Chagas Institute, FIOCRUZ PR, Curitiba 81350-010, Brazil.ORCID 0000-0002-1972-2658
Fundação Carlos Chagas · BRAlbert Einstein College of Medicine · USUniversidade de São Paulo · BRUniversidade Federal do Rio Grande do Sul · BRUniversidade Federal do Rio de Janeiro · BR

Funding

Antibody differentially alters Histoplasma extracellular vesiclesR21AI124797 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI NOSANCHUK, JOSHUA D · 2016 to 2017
$538k
National Council for Scientific and Technological Development 301304/2017-3National Council for Scientific and Technological Development 405520/2018-2National Council for Scientific and Technological Development 442317/2019-0NIAID NIH HHS R21 AI124797NIH HHS AI124797Oswaldo Cruz Foundation VPPCB-007-FIO-18Oswaldo Cruz Foundation VPPCB-07-FIO-18-2-52Oswaldo Cruz Foundation VPPIS-001-FIO18
6 · The paper itself

Abstract

Antifungal resistance has become more frequent, either due to the emergence of naturally resistant species or the development of mechanisms that lead to resistance in previously susceptible species. Among these fungal species of global threat,

Indexed as

Candida aurisdrug resistanceextracellular vesiclesproteinRNA

Identifiers

PMID36294557
PMCPMC9605528
OpenAlexW4296629151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.