Evidence map›Paper›PMID 36294528›Full record

ReviewJournal of clinical medicine2022

Concomitant Endoscopic Surgery for Bladder Tumors and Prostatic Obstruction: Are We Safely Hitting Two Birds with One Stone? A Systematic Review and Meta-Analysis.

Eliophotos Savvides, Nikolaos Pyrgidis, Georgios Langas, Evangelos N Symeonidis, Georgios Dimitriadis, Petros Sountoulides

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Eliophotos Savvides1st Department of Urology, Faculty of Health Sciences, Medical School, Aristotle University of Thessaloniki, GR-55134 Thessaloniki, Greece.ORCID 0000-0002-4719-9462
Nikolaos PyrgidisDepartment of Urology, 'Martha-Maria' Hospital Nuremberg, 90402 Nuremberg, Germany.ORCID 0000-0002-7707-8426
Georgios Langas1st Department of Urology, Faculty of Health Sciences, Medical School, Aristotle University of Thessaloniki, GR-55134 Thessaloniki, Greece.ORCID 0000-0002-7684-1151
Evangelos N Symeonidis1st Department of Urology, Faculty of Health Sciences, Medical School, Aristotle University of Thessaloniki, GR-55134 Thessaloniki, Greece.ORCID 0000-0002-6360-0762
Georgios Dimitriadis1st Department of Urology, Faculty of Health Sciences, Medical School, Aristotle University of Thessaloniki, GR-55134 Thessaloniki, Greece.
Petros Sountoulides1st Department of Urology, Faculty of Health Sciences, Medical School, Aristotle University of Thessaloniki, GR-55134 Thessaloniki, Greece.ORCID 0000-0003-2671-571X
Aristotle University of Thessaloniki · GRMartha-Maria Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLower urinary tract symptoms (LUTS) caused by benign prostatic obstruction (BPO) and bladder tumors may co-exist, especially among elderly patients. Transurethral resection of bladder tumors (TURBT) and endoscopic surgery for benign prostatic obstruction in the same setting are avoided by many surgeons due to concerns for tumor cell seeding and recurrences in the prostatic urethra.

aimThe aim of this study was assess the effect of concomitant TURBT and endoscopic BPO surgery on oncological safety and patient quality of life via systematic review and meta-analysis.

methodsWe searched the PubMed, Cochrane Library, EMBASE, Scopus, and Clinicaltrials.gov databases and sources of grey literature published before June 2021 for relevant studies. We performed a random-effects meta-analysis of odds ratios (ORs) or weighted mean differences (WMD) to compare concomitant TURBT and BPO surgery versus TURBT alone in terms of recurrence and progression rates. Accordingly, we undertook multiple subgroups and sensitivity analyses (PROSPERO: CRD42020173363).

resultsThree randomized and twelve retrospective observational studies with 2421 participants were included. Across studies with good methodological quality, no statistically significant differences were demonstrated regarding overall bladder tumors recurrence rates between concomitant endoscopic BPO surgery and TURBT versus TURBT alone (OR: 0.81, 95% CI: 0.60-1.09, I

conclusionConcomitant endoscopic BPO surgery and TURBT are oncologically safe and improve LUTS-related quality of life.

Indexed as

benign prostatic obstructionbladder cancerconcomitantrecurrencetransurethral resection

Identifiers

PMID36294528
PMCPMC9604964
OpenAlexW4307262210

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.