Evidence map›Paper›PMID 36294434›Full record

ArticleJournal of clinical medicine2022

Prevalence of Osteoporosis Assessed by DXA and/or CT in Severe Obese Patients.

Marion Halin, Edem Allado, Eliane Albuisson, Laurent Brunaud, Isabelle Chary-Valckenaere, Damien Loeuille, Didier Quilliot, Marine Fauny

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Marion HalinDepartment of Rheumatology, University Hospital, F-54000 Nancy, France.
Edem AlladoUniversity Center of Sports Medicine and Adapted Physical Activity, CHRU-Nancy, F-54000 Nancy, France.ORCID 0000-0002-1760-6979
Eliane AlbuissonUnité de Méthodologie, Data Management et Statistiques (UMDS), Département MPI, DRCI, CHRU-Nancy, F-54000 Nancy, France.ORCID 0000-0002-1490-7549
Laurent BrunaudUnité Multidisciplinaire de la Chirurgie de L'obésité (UMCO), University Hospital, F-54000 Nancy, France.ORCID 0000-0001-5182-6660
Isabelle Chary-ValckenaereDepartment of Rheumatology, University Hospital, F-54000 Nancy, France.
Damien LoeuilleDepartment of Rheumatology, University Hospital, F-54000 Nancy, France.
Didier QuilliotUnité Multidisciplinaire de la Chirurgie de L'obésité (UMCO), University Hospital, F-54000 Nancy, France.
Marine FaunyDepartment of Rheumatology, University Hospital, F-54000 Nancy, France.ORCID 0000-0002-5790-0531
Centre National de la Recherche Scientifique · FRCentre Hospitalier Régional et Universitaire de Nancy · FRInserm · FRDéveloppement, Adaptation et Handicap

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The primary objective was to evaluate bone fragility prevalence on dual X-ray absorptiometry (DXA) and computed tomography (CT) in patients with severe obesity. The secondary objective was to evaluate the risk factors for bone fragility. This monocentric study was conducted in patients with grade 2 and 3 obesity. Bone mineral density (BMD) and T-score were studied on DXA, and the scanographic bone attenuation coefficient of L1 (SBAC-L1) was measured on CT. Among the 1386 patients included, 1013 had undergone both DXA and CT within less than 2 years. The mean age was 48.4 (±11.4) years, 77.6% were women, and the mean BMI was 45.6 (±6.7) kg/m². Eight patients (0.8%) had osteoporosis in at least one site. The mean SBAC-L1 was 192.3 (±52.4) HU; 163 patients (16.1%) were under the threshold of 145 HU. Older age (OR[CI95] = 1.1 [1.08-1.16]), lower BMD on the femoral neck and spine (OR[CI95] = 0.04[0.005-0.33] and OR[CI95] = 0.001[0.0001-0.008], respectively), and higher lean mass (OR[CI95] = 1.1 [1.03-1.13]) were significantly associated with an SBAC-L1 ≤ 145 HU in multivariate analysis. Approximately 16% of patients with severe obesity were under the SBAC-L1 threshold, while less than 1% were classified as osteoporotic on DXA.

Indexed as

bone mineral density (BMD)dual-energy X-ray absorptiometry (DXA)obesityscanographic bone attenuation coefficient (SBAC-L1)tomodensitometry/CT

Identifiers

PMID36294434
PMCPMC9605130
OpenAlexW4306658837

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.