Evidence map›Paper›PMID 36294094›Full record

ArticleInternational journal of environmental research and public health2022

Mortality Risk Stratification in Emergency Surgery for Obstructive Colon Cancer-External Validation of International Scores, American College of Surgeons National Surgical Quality Improvement Program Surgical Risk Calculator (SRC), and the Dedicated Score of French Surgical Association (AFC/OCC Score).

Raul Mihailov, Dorel Firescu, Georgiana Bianca Constantin, Oana Mariana Mihailov, Petre Hoara, Rodica Birla, Traian Patrascu, Eugenia Panaitescu

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Raul MihailovClinic Surgery Department, Dunarea de Jos University, 800216 Galati, Romania.ORCID 0000-0001-7081-9490
Dorel FirescuClinic Surgery Department, Dunarea de Jos University, 800216 Galati, Romania.
Georgiana Bianca ConstantinMorphological and Functional Sciences Department, Dunarea de Jos University, 800216 Galati, Romania.
Oana Mariana MihailovClinic Medical Department, Dunarea de Jos University, 800216 Galati, Romania.
Petre HoaraGeneral Surgery Department, Carol Davila University, 050474 Bucharest, Romania.
Rodica BirlaGeneral Surgery Department, Carol Davila University, 050474 Bucharest, Romania.ORCID 0000-0002-8799-4524
Traian PatrascuGeneral Surgery Department, Carol Davila University, 050474 Bucharest, Romania.
Eugenia PanaitescuMedical Informatics and Biostatistics Department, Carol Davila University, 050474 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · RO"Dunarea de Jos" University of Galati · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe increased rates of postoperative mortality after emergency surgery for obstructive colon cancer (OCC) require the use of risk-stratification scores. The study purpose is to external validate the surgical risk calculator (SRC) and the AFC/OCC score and to create a score for risk stratification. PATIENTS AND

methodsOverall, 435 patients with emergency surgery for OCC were included in this retrospective study. We used statistical methods suitable for the aimed purpose.

resultsPostoperative mortality was 11.72%. SRC performance: strong discrimination (AUC = 0.864) and excellent calibration (11.80% predicted versus 11.72% observed); AFC/OCC score performance: adequate discrimination (AUC = 0.787) and underestimated mortality (6.93% predicted versus 11.72% observed). We identified nine predictors of postoperative mortality: age > 70 years, CHF, ECOG > 2, sepsis, obesity or cachexia, creatinine (aN) or platelets (aN), and proximal tumors (AUC = 0.947). Based on the score, we obtained four risk groups of mortality rate: low risk (0.7%)-0-2 factors, medium risk (12.5%)-3 factors, high risk (40.0%)-4 factors, very high risk (84.4%)-5-6 factors.

conclusionsThe two scores were externally validated. The easy identification of predictors and its performance recommend the mortality score of the Clinic County Emergency Hospital of Galați/OCC for clinical use.

Indexed as

Colonic NeoplasmsSurgeonsAgedCreatinineHumansQuality ImprovementRetrospective StudiesRisk AssessmentRisk FactorsUnited StatesCreatinineemergency careexternal validationobstructive colon cancerprediction

Identifiers

PMID36294094
PMCPMC9603747
OpenAlexW4306837115

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.