Evidence map›Paper›PMID 36294037›Full record

SynthesisInternational journal of environmental research and public health2022

Does Early Childhood Caries Increase Caries Development among School Children and Adolescents? A Systematic Review and Meta-Analysis.

Phoebe Pui Ying Lam, Helene Chua, Manikandan Ekambaram, Edward Chin Man Lo, Cynthia Kar Yung Yiu

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Key Factors Influencing Caries Development in Preschoolers: A Focus on Socio-Demographic, Maternal Health, and Salivary Biomarkers in 3-Year-Olds.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Observational
  14. Article
  15. Editorial: Improving children's oral health.Frontiers in oral health · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Phoebe Pui Ying LamPaediatric Dentistry, Faculty of Dentistry, The University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0002-2468-2080
Helene ChuaAuckland District Health Board, Auckland 1051, New Zealand.ORCID 0000-0001-7322-6113
Manikandan EkambaramPaediatric Dentistry, Faculty of Dentistry, University of Otago, Dunedin 9016, New Zealand.ORCID 0000-0002-9156-3727
Edward Chin Man LoApplied Oral Sciences & Community Dental Care, Faculty of Dentistry, The University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0002-3618-0619
Cynthia Kar Yung YiuPaediatric Dentistry, Faculty of Dentistry, The University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0003-4090-6205
University of Hong Kong · HKAuckland District Health Board · NZUniversity of Otago · NZ

Funding

Hong Kong Health and Medical Research Fund (HMRF) Grant 16172221
6 · The paper itself

Abstract

The aim of this paper is to systematically review the literature to determine whether early childhood caries (ECC) is significantly associated with caries development in permanent teeth among school children and adolescents, and to identify the association of other risk factors over 24 months. A systematic literature search was performed in four electronic databases and via a manual search from inception to 28 July 2022. Independent study selection and screening, data extraction, evaluation of risk of bias using ROBINS-I tool and certainty of evidence with GRADE were performed. Ten cohort studies were included, all of which identified that ECC significantly increased the risk of caries in permanent teeth. Meta-analysis suggested children with ECC were three times more likely to develop caries in their permanent teeth (OR, 3.22; 95% CI 2.80, 3.71;

Indexed as

Dental CariesFrailtyAdolescentBiasChildChild, PreschoolDental Caries SusceptibilityDentition, PermanentHumansRisk Factorsadolescentsdental cariesEarly Childhood Cariessocial inequalitysystematic review

Identifiers

PMID36294037
PMCPMC9603429
OpenAlexW4306742393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.