Evidence map›Paper›PMID 36293571›Full record

ArticleInternational journal of environmental research and public health2022

Mixture Risk Assessment of Complex Real-Life Mixtures-The PANORAMIX Project.

Beate I Escher, Marja Lamoree, Jean-Philippe Antignac, Martin Scholze, Matthias Herzler, Timo Hamers, Tina Kold Jensen, Marc Audebert, Francois Busquet, Dieter Maier and 15 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Prenatal exposure to multiple environmental chemicals and birth size.Journal of exposure science & environmental epidemiology · 2024
    Article
  6. Article
  7. Analysis of gasoline-related pollutant exposures and risks in California between 1996 and 2014.Journal of exposure science & environmental epidemiology · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Beate I EscherDepartment of Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, DE-04318 Leipzig, Germany.ORCID 0000-0002-5304-706X
Marja LamoreeDepartment Environment & Health, Faculty of Science, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0002-7373-7738
Jean-Philippe AntignacLABERCA, Oniris, INRAE, 44307 Nantes, France.ORCID 0000-0001-9512-9314
Martin ScholzeCentre for Pollution Research and Policy, Environmental Sciences Division, Brunel University London, Kingston Lane, Uxbridge UB8 3PH, UK.
Matthias HerzlerGerman Federal Institute for Risk Assessment (BfR), 10589 Berlin, Germany.ORCID 0000-0001-5636-8152
Timo HamersDepartment Environment & Health, Faculty of Science, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.
Tina Kold JensenDepartment of Environmental Medicine, University of Southern Denmark, DK-5000 Odense, Denmark.
Marc AudebertToxalim, UMR1331, INRAE, 31027 Toulouse, France.ORCID 0000-0001-7898-6912
Francois BusquetAltertox Academy, 1050 Brussels, Belgium.
Dieter MaierBiomax Informatics AG, 82152 Planegg, Germany.
Michael OelgeschlägerGerman Federal Institute for Risk Assessment (BfR), 10589 Berlin, Germany.
Maria João ValenteNational Food Institute, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark.
Henriette BoyeOdense Child Cohort, Hans Christian Andersen Hospital for Children, Odense University Hospital, DK-5000 Odense, Denmark.
Sebastian SchmeisserGerman Federal Institute for Risk Assessment (BfR), 10589 Berlin, Germany.
Gaud DervillyLABERCA, Oniris, INRAE, 44307 Nantes, France.ORCID 0000-0002-1867-0008
Matteo PiumattiAltertox Academy, 1050 Brussels, Belgium.
Soléne MotteauLABERCA, Oniris, INRAE, 44307 Nantes, France.
Maria KönigDepartment of Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, DE-04318 Leipzig, Germany.
Kostja RenkoGerman Federal Institute for Risk Assessment (BfR), 10589 Berlin, Germany.ORCID 0000-0003-2050-0961
Maria MargalefDepartment Environment & Health, Faculty of Science, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0001-7932-9770
Ronan CariouLABERCA, Oniris, INRAE, 44307 Nantes, France.
Yanying MaNational Food Institute, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark.
Andreas Frederik TreschowNational Food Institute, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark.
Andreas KortenkampCentre for Pollution Research and Policy, Environmental Sciences Division, Brunel University London, Kingston Lane, Uxbridge UB8 3PH, UK.
Anne Marie VinggaardNational Food Institute, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark.ORCID 0000-0002-6822-3572

Funding

European Union 101036631
6 · The paper itself

Abstract

Humans are involuntarily exposed to hundreds of chemicals that either contaminate our environment and food or are added intentionally to our daily products. These complex mixtures of chemicals may pose a risk to human health. One of the goals of the European Union's Green Deal and zero-pollution ambition for a toxic-free environment is to tackle the existent gaps in chemical mixture risk assessment by providing scientific grounds that support the implementation of adequate regulatory measures within the EU. We suggest dealing with this challenge by: (1) characterising 'real-life' chemical mixtures and determining to what extent they are transferred from the environment to humans via food and water, and from the mother to the foetus; (2) establishing a high-throughput whole-mixture-based

Indexed as

Complex MixturesEnvironmental PollutionOrganic ChemicalsEuropean UnionHumansRisk AssessmentComplex MixturesOrganic Chemicalsdevelopmental neurotoxicityeffect-based trigger valueseffect-directed analysismixture risk assessmentnew methodological approachesPANORAMIXreal-life mixturesreproductive toxicity

Identifiers

PMID36293571
PMCPMC9602166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.