Evidence map›Paper›PMID 36293559›Full record

ArticleInternational journal of molecular sciences2022

Effects of Sub-Minimum Inhibitory Concentrations of Imipenem and Colistin on Expression of Biofilm-Specific Antibiotic Resistance and Virulence Genes in

Abebe Mekuria Shenkutie, Jiaying Zhang, Mianzhi Yao, Daniel Asrat, Franklin W N Chow, Polly H M Leung

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. A Novel Method to Monitor the Evolution of Antimicrobial Resistance inInternational journal of molecular sciences · 2026
    Article
  4. Article
  5. Review
  6. Antibiotics (Basel, Switzerland) · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Drug design, development and therapy · 2024
    Article
  11. Phenotypic Traits and Probiotic Functions ofFoods (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Genomics: Infectious Disease and Host-Pathogen Interaction.International journal of molecular sciences · 2023
    Article
  14. Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Abebe Mekuria ShenkutieDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, China.ORCID 0000-0002-6717-3948
Jiaying ZhangDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, China.
Mianzhi YaoDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, China.
Daniel AsratDepartment of Microbiology, Immunology, and Parasitology, School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa P.O. Box 9086, Ethiopia.ORCID 0000-0003-0066-124X
Franklin W N ChowDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, China.ORCID 0000-0003-1275-2464
Polly H M LeungDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, China.ORCID 0000-0003-2406-4773
Hong Kong Polytechnic University · HKAddis Ababa University · ET

Funding

the Hong Kong PhD Fellowship Scheme PH16-01625
6 · The paper itself

Abstract

Antibiotics at suboptimal doses promote biofilm formation and the development of antibiotic resistance. The underlying molecular mechanisms, however, were not investigated. Here, we report the effects of sub-minimum inhibitory concentrations (sub-MICs) of imipenem and colistin on genes associated with biofilm formation and biofilm-specific antibiotic resistance in a multidrug-tolerant clinical strain of

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsBiofilmsColistinDNA GyraseDrug Resistance, Multiple, BacterialHumansImipenemMicrobial Sensitivity TestsVirulenceAnti-Bacterial AgentsColistinDNA GyraseImipenemAcinetobacter baumanniiantibiotic resistancebiofilmcolistinimipenemRNA sequencingsmall RNAvirulence

Identifiers

PMID36293559
PMCPMC9603859
OpenAlexW4307262701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.