Evidence map›Paper›PMID 36293510›Full record

ReviewInternational journal of molecular sciences2022

The Central Nervous Mechanism of Stress-Promoting Cancer Progression.

Yuchuan Hong, Lu Zhang, Nian Liu, Xirong Xu, Dan Liu, Jie Tu

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Survivorship Challenges and Supportive Care in Lung Cancer.Seminars in respiratory and critical care medicine · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yuchuan HongShenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases, CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Shenzhen 518055, China.ORCID 0000-0002-5497-2548
Lu ZhangShenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases, CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Shenzhen 518055, China.
Nian LiuShenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases, CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Shenzhen 518055, China.
Xirong XuShenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases, CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Shenzhen 518055, China.
Dan LiuShenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases, CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Shenzhen 518055, China.
Jie TuShenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases, CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Shenzhen 518055, China.ORCID 0000-0002-1432-5784
Chinese Academy of Sciences · CN

Funding

China Postdoctoral Science Foundation 2021M703374 DLNational Natural Science Foundation of China 31671116 JTNational Natural Science Foundation of China 31761163005 JTProgram of Shenzhen Science and Technology Innovation Commission JCYJ20200109150717745 LZthe Guangdong Provincial Key S&T Program 2018B030336001 JTthe Key Basic Research Program of Shenzhen Science and Technology Innovation Commission JCYJ20200109115405930the Key Basic Research Program of Shenzhen Science and Technology Innovation Commission JCYJ 20210324115811031 YHthe Science and Technology Program of Guangzhou 202007030001 JTthe Shenzhen Science and Technology Program JCYJ20210324101813035 DL
6 · The paper itself

Abstract

Evidence shows that stress can promote the occurrence and development of tumors. In recent years, many studies have shown that stress-related hormones or peripheral neurotransmitters can promote the proliferation, survival, and angiogenesis of tumor cells and impair the body's immune response, causing tumor cells to escape the "surveillance" of the immune system. However, the perception of stress occurs in the central nervous system (CNS) and the role of the central nervous system in tumor progression is still unclear, as are the underlying mechanisms. This review summarizes what is known of stress-related CNS-network activation during the stress response and the influence of the CNS on tumors and discusses available adjuvant treatment methods for cancer patients with negative emotional states, such as anxiety and depression.

Indexed as

NeoplasmsCentral Nervous SystemHormonesHumansHypothalamo-Hypophyseal SystemImmune SystemNeurotransmitter AgentsPituitary-Adrenal SystemStress, PsychologicalHormonesNeurotransmitter Agentsadrenergic receptorcancercentral nervous systemglucocorticoid receptorHPA axisneuropeptide Y receptorstresssympathetic nervous system

Identifiers

PMID36293510
PMCPMC9604265
OpenAlexW4307262486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.