Evidence map›Paper›PMID 36293491›Full record

ArticleInternational journal of molecular sciences2022

Experimental Evaluation of Quantum Dots and Antibodies Conjugation by Surface Plasmon Resonance Spectroscopy.

Anton Popov, Viktorija Lisyte, Asta Kausaite-Minkstimiene, Eiva Bernotiene, Almira Ramanaviciene

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Methods for Conjugating Antibodies with Quantum Dots.Molecules (Basel, Switzerland) · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anton PopovDepartment of Immunology, State Research Institute Centre for Innovative Medicine, Santariskiu Str. 5, LT-08406 Vilnius, Lithuania.ORCID 0000-0002-9867-1931
Viktorija LisyteNanoTechnas-Center of Nanotechnology and Materials Science, Institute of Chemistry, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko Str. 24, LT-03225 Vilnius, Lithuania.
Asta Kausaite-MinkstimieneDepartment of Immunology, State Research Institute Centre for Innovative Medicine, Santariskiu Str. 5, LT-08406 Vilnius, Lithuania.
Eiva BernotieneDepartment of Regenerative Medicine, State Research Institute Centre for Innovative Medicine, Santariskiu Str. 5, LT-08406 Vilnius, Lithuania.
Almira RamanavicieneDepartment of Immunology, State Research Institute Centre for Innovative Medicine, Santariskiu Str. 5, LT-08406 Vilnius, Lithuania.ORCID 0000-0001-5864-0359

Funding

Lietuvos Mokslo Taryba . 09.3.3-LMT-K-712-19-0170
6 · The paper itself

Abstract

The application of antibody-functionalized quantum dots (QDs) in different areas has been widely described in the literature. However, a standard routine method for obtaining information on the conjugation efficiency of QDs with antibodies in terms of the interaction of the functionalized QDs with a specific antigen is still lacking. Herein, surface plasmon resonance (SPR) spectroscopy is proposed for this purpose. Gold-coated SPR sensor disks were modified with a self-assembled monolayer of 11-mercaptoundecanoic acid, and carbodiimide cross-linker chemistry was used to covalently immobilize the CD44 biomarker on the premodified surface (Au/CD44). Meanwhile, QDs functionalized with amine-derivatized polyethylene glycol (PEG) (QDs-NH

Indexed as

Quantum DotsAminesAntibodiesCarbodiimidesGoldPolyethylene GlycolsSpectrum AnalysisSurface Plasmon ResonanceAminesAntibodiesCarbodiimidesGoldPolyethylene GlycolsantibodyCD44conjugationquantum dotssurface plasmon resonance

Identifiers

PMID36293491
PMCPMC9603974

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.