Evidence map›Paper›PMID 36293479›Full record

ArticleInternational journal of molecular sciences2022

A Role of DNA Methylation within the CYP17A1 Gene in the Association of Genetic and Environmental Risk Factors with Stress-Related Manifestations of Schizophrenia.

Margarita Alfimova, Nikolay Kondratyev, Galina Korovaitseva, Tatyana Lezheiko, Victoria Plakunova, Marina Gabaeva, Vera Golimbet

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. DNA methylation and prediction of biological age.Frontiers in molecular biosciences · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Margarita AlfimovaMental Health Research Center, 115522 Moscow, Russia.
Nikolay KondratyevMental Health Research Center, 115522 Moscow, Russia.ORCID 0000-0002-5134-6007
Galina KorovaitsevaMental Health Research Center, 115522 Moscow, Russia.
Tatyana LezheikoMental Health Research Center, 115522 Moscow, Russia.
Victoria PlakunovaMental Health Research Center, 115522 Moscow, Russia.ORCID 0000-0001-8690-5422
Marina GabaevaMental Health Research Center, 115522 Moscow, Russia.
Vera GolimbetMental Health Research Center, 115522 Moscow, Russia.
Mental Health Research Center of Russian Academy of Medical Sciences · RU

Funding

Russian Science Foundation 16-15-00056Russian Science Foundation 21-15-00124
6 · The paper itself

Abstract

As genetic and environmental influences on schizophrenia might converge on DNA methylation (DNAm) within loci which are both associated with the disease and implicated in response to environmental stress, we examined whether DNAm within

Indexed as

DNA MethylationSchizophreniaEpigenesis, GeneticHumansMethyltransferasesMinisatellite RepeatsPolymorphism, Single NucleotideRisk FactorsSteroid 17-alpha-HydroxylaseAS3MT protein, humanCYP17A1 protein, humanMethyltransferasesSteroid 17-alpha-HydroxylaseAS3MTCYP17A1DNA methylationexecutive functionsrisk locusschizophreniastress

Identifiers

PMID36293479
PMCPMC9604497
OpenAlexW4306925937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.