Evidence map›Paper›PMID 36293415›Full record

ArticleInternational journal of molecular sciences2022

Graphene Quantum Dots Modified Upconversion Nanoparticles for Photodynamic Therapy.

Yuting Li, Yufei Wang, Hong Shang, Jing Wu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Carbonaceous Nanomaterials for Phototherapy of Cancer.Technology in cancer research & treatment
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuting LiSchool of Science, China University of Geosciences (Beijing), Beijing 100083, China.
Yufei WangSchool of Science, China University of Geosciences (Beijing), Beijing 100083, China.
Hong ShangSchool of Science, China University of Geosciences (Beijing), Beijing 100083, China.
Jing WuSchool of Science, China University of Geosciences (Beijing), Beijing 100083, China.ORCID 0000-0001-5954-2793

Funding

Beijing Natural Science Foundation 2222022Fundamental Research Funds for the Central Universities 2652019112 and 2652018004National Natural Science Foundation of China 21874120 and 22001240
6 · The paper itself

Abstract

Photodynamic therapy (PDT), as a novel technique, has been extensively employed in cancer treatment by utilizing reactive oxygen species (ROS) to kill malignant cells. However, most photosensitizers (PSs) are short of ROS yield and affect the therapeutic effect of PDT. Thus, there is a substantial demand for the development of novel PSs for PDT to advance its clinical translation. In this study, we put forward a new strategy for PS synthesis via modifying graphene quantum dots (GQDs) on the surface of rare-earth elements doped upconversion nanoparticles (UCNPs) to produce UCNPs@GQDs with core-shell structure. This new type of PSs combined the merits of UCNPs and GQDs and produced ROS efficiently under near-infrared light excitation to trigger the PDT process. UCNPs@GQDs exhibited high biocompatibility and obvious concentration-dependent PDT efficiency, shedding light on nanomaterials-based PDT development.

Indexed as

GraphiteNanoparticlesPhotochemotherapyQuantum DotsPhotosensitizing AgentsReactive Oxygen SpeciesGraphitePhotosensitizing AgentsReactive Oxygen Speciesgraphene quantum dotsphotodynamic therapyphotosensitizerreactive oxygen speciesupconversion nanoparticles

Identifiers

PMID36293415
PMCPMC9604409

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.