Evidence map›Paper›PMID 36293406›Full record

ReviewInternational journal of molecular sciences2022

Chemiluminescence in Combination with Organic Photosensitizers: Beyond the Light Penetration Depth Limit of Photodynamic Therapy.

Jie Gao, Zhengjun Chen, Xinmin Li, Mingyan Yang, Jiajia Lv, Hongyu Li, Zeli Yuan

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Sequential HAngewandte Chemie (International ed. in English) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Advancements and emerging trends in photodynamic therapy: innovations in cancer treatment and beyond.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Review
  11. Article
  12. Review
  13. Phototherapy in cancer treatment: strategies and challenges.Signal transduction and targeted therapy · 2025
    Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jie GaoKey Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, No.6 West Xuefu Road, Xinpu District, Zunyi 563000, China.ORCID 0000-0002-6143-6284
Zhengjun ChenKey Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, No.6 West Xuefu Road, Xinpu District, Zunyi 563000, China.
Xinmin LiKey Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, No.6 West Xuefu Road, Xinpu District, Zunyi 563000, China.ORCID 0000-0002-5544-793X
Mingyan YangKey Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, No.6 West Xuefu Road, Xinpu District, Zunyi 563000, China.
Jiajia LvKey Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, No.6 West Xuefu Road, Xinpu District, Zunyi 563000, China.
Hongyu LiKey Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, No.6 West Xuefu Road, Xinpu District, Zunyi 563000, China.ORCID 0000-0001-7359-678X
Zeli YuanKey Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, No.6 West Xuefu Road, Xinpu District, Zunyi 563000, China.ORCID 0000-0001-5354-769X

Funding

Cultivation project plan of new seedling cultivation and innovation exploration special project of Zunyi Medical University, Platform talents of Qiankehe [2018] No. 5772-030Guizhou Science and Technology Plan Qianke He Foundation-ZK[2021] General 035Guizhou Science and Technology Support Program [2020]4Y158Innovative Group Project of Guizhou Province of Education KY[2018]024Natural Science Foundation of China 81360471Natural Science Foundation of China 82060626Talents of Guizhou Science and Technology Cooperation Platform [2020]4104Zunyi Science and Technology Plan (Zunshikehe HZ Zi(2020)46, Platform talents of Qiankehe [2018]5772-053
6 · The paper itself

Abstract

Photodynamic therapy (PDT) is a promising noninvasive medical technology that has been approved for the treatment of a variety of diseases, including bacterial and fungal infections, skin diseases, and several types of cancer. In recent decades, many photosensitizers have been developed and applied in PDT. However, PDT is still limited by light penetration depth, although many near-infrared photosensitizers have emerged. The chemiluminescence-mediated PDT (CL-PDT) system has recently received attention because it does not require an external light source to achieve targeted PDT. This review focuses on the rational design of organic CL-PDT systems. Specifically, PDT types, light wavelength, the chemiluminescence concept and principle, and the design of CL-PDT systems are introduced. Furthermore, chemiluminescent fraction examples, strategies for combining chemiluminescence with PDT, and current cellular and animal applications are highlighted. Finally, the current challenges and possible solutions to CL-PDT systems are discussed.

Indexed as

NeoplasmsPhotochemotherapyAnimalsLuminescencePhotosensitizing AgentsPhotosensitizing Agentschemiluminescencechemiluminescence resonance energy transferphotodynamic therapyphotosensitizerreactive oxygen species

Identifiers

PMID36293406
PMCPMC9604449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.