Evidence map›Paper›PMID 36293377›Full record

ArticleInternational journal of molecular sciences2022

Global Proteomic Profile of Aluminum-Induced Hippocampal Impairments in Rats: Are Low Doses of Aluminum Really Safe?

Leonardo Oliveira Bittencourt, Rakhel Dayanne Damasceno-Silva, Walessa Alana Bragança Aragão, Luciana Eiró-Quirino, Ana Carolina Alves Oliveira, Rafael Monteiro Fernandes, Marco Aurelio M Freire, Sabrina Carvalho Cartágenes, Aline Dionizio, Marília Afonso Rabelo Buzalaf and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Leonardo Oliveira BittencourtLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém 66075110, Brazil.ORCID 0000-0002-9525-2723
Rakhel Dayanne Damasceno-SilvaLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém 66075110, Brazil.ORCID 0000-0003-3944-8104
Walessa Alana Bragança AragãoLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém 66075110, Brazil.ORCID 0000-0003-4578-1106
Luciana Eiró-QuirinoLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém 66075110, Brazil.
Ana Carolina Alves OliveiraLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém 66075110, Brazil.
Rafael Monteiro FernandesLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém 66075110, Brazil.
Marco Aurelio M FreireGraduate Program in Health and Society, Faculty of Health Sciences, State University of Rio Grande do Norte (UERN), Mossoro 59610210, Brazil.ORCID 0000-0002-6483-0498
Sabrina Carvalho CartágenesLaboratory of Pharmacology of Inflammation and Behavior, Institute of Health Sciences, Federal University of Pará, Belém 66075110, Brazil.
Aline DionizioDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 05508060, Brazil.ORCID 0000-0002-8687-0124
Marília Afonso Rabelo BuzalafDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 05508060, Brazil.ORCID 0000-0002-5985-3951
Juliana Silva CassoliInstitute of Biological Sciences, Federal University of Pará, Belém 66075110, Brazil.ORCID 0000-0002-2174-6309
Ana CirovicFaculty of Medicine, Institute of Anatomy, University of Belgrade, 11000 Belgrade, Serbia.
Aleksandar CirovicFaculty of Medicine, Institute of Anatomy, University of Belgrade, 11000 Belgrade, Serbia.
Cristiane do Socorro Ferraz MaiaLaboratory of Pharmacology of Inflammation and Behavior, Institute of Health Sciences, Federal University of Pará, Belém 66075110, Brazil.ORCID 0000-0003-4493-7375
Rafael Rodrigues LimaLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém 66075110, Brazil.ORCID 0000-0003-1486-4013
Universidade Federal do Pará · BRUniversidade de São Paulo · BRUniversity of Belgrade · RSUniversidade do Estado do Rio Grande do Norte · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hippocampus is the brain area where aluminum (Al) accumulates in abundance and is widely associated with learning and memory. In the present study, we evaluate behavioral, tissue, and proteomic changes in the hippocampus of Wistar rats caused by exposure to doses that mimic human consumption of aluminum chloride (AlCl

Indexed as

AluminumProteomicsAluminum ChlorideAluminum CompoundsAnimalsHippocampusHumansMaleRatsRats, WistarAluminumAluminum ChlorideAluminum Compoundsaluminumhippocampusneurotoxicity

Identifiers

PMID36293377
PMCPMC9603961
OpenAlexW4306838530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.