Evidence map›Paper›PMID 36293331›Full record

ArticleInternational journal of molecular sciences2022

Sensitivity of Cutaneous T-Cell Lymphoma Cells to the Mcl-1 Inhibitor S63845 Correlates with the Lack of Bcl-w Expression.

Uly Sumarni, Jiaqi Zhu, Tobias Sinnberg, Jürgen Eberle

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Uly SumarniDepartment of Dermatology, Venerology und Allergology, Skin Cancer Center, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Jiaqi ZhuDepartment of Dermatology, Venerology und Allergology, Skin Cancer Center, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Tobias SinnbergDepartment of Dermatology, Venerology und Allergology, Skin Cancer Center, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.ORCID 0000-0003-3922-3327
Jürgen EberleDepartment of Dermatology, Venerology und Allergology, Skin Cancer Center, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.ORCID 0000-0001-8533-1519
Charité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-term, curative treatment of cutaneous T-cell lymphomas (CTCL) remains a major challenge. Therapy resistance is often based on apoptosis deficiency, and may depend on antiapoptotic Bcl-2 proteins, such as Bcl-2, Bcl-x

Indexed as

Antineoplastic AgentsLymphoma, T-Cell, CutaneousAniline CompoundsApoptosisbcl-X ProteinBiphenyl CompoundsCaspasesCell Line, TumorHumansMyeloid Cell Leukemia Sequence 1 ProteinNitrophenolsPiperazinesProto-Oncogene Proteins c-bcl-2PyrimidinesSulfonamidesThiophenesABT-737Aniline CompoundsAntineoplastic Agentsbcl-X ProteinBiphenyl CompoundsCaspasesMyeloid Cell Leukemia Sequence 1 ProteinnavitoclaxNitrophenolsPiperazinesProto-Oncogene Proteins c-bcl-2PyrimidinesS63845SulfonamidesThiophenesBcl-2 proteinsBH3 mimeticsnon-Hodgkin lymphoma

Identifiers

PMID36293331
PMCPMC9604298
OpenAlexW4306741943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.