Evidence map›Paper›PMID 36293249›Full record

ArticleInternational journal of molecular sciences2022

The Antimicrobial Peptide 1018-K6 Interacts Distinctly with Eukaryotic and Bacterial Membranes, the Basis of Its Specificity and Bactericidal Activity.

Rosa Luisa Ambrosio, Catalina Ana Rosselló, Doralicia Casares, Gianna Palmieri, Aniello Anastasio, Pablo V Escribá

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
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  5. Article
  6. Membrane-Peptide Interactions: From Basics to Current Applications 2.0.International journal of molecular sciences · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Rosa Luisa AmbrosioDepartment of Veterinary Medicine and Animal Production, Unit of Food Hygiene, University of Naples Federico II, Via Delpino 1, 80137 Naples, Italy.ORCID 0000-0002-4413-142X
Catalina Ana RossellóLaboratory of Molecular Cell Biomedicine, University of the Balearic Islands, 07122 Palma, Spain.ORCID 0000-0002-8977-607X
Doralicia CasaresLaboratory of Molecular Cell Biomedicine, University of the Balearic Islands, 07122 Palma, Spain.ORCID 0000-0002-2314-3026
Gianna PalmieriInstitute of Biosciences and BioResources, National Research Council (IBBR-CNR), 80131 Napoli, Italy.ORCID 0000-0002-9007-4075
Aniello AnastasioDepartment of Veterinary Medicine and Animal Production, Unit of Food Hygiene, University of Naples Federico II, Via Delpino 1, 80137 Naples, Italy.
Pablo V EscribáLaboratory of Molecular Cell Biomedicine, University of the Balearic Islands, 07122 Palma, Spain.ORCID 0000-0001-9795-182X
Universitat de les Illes Balears · ESUniversity of Naples Federico II · ITInstitute of Biosciences and Bioresources · IT

Funding

European Commission H2020 Framework Programme 755179European Social Funds Grant ES01/TCAI/24_2018Govern de les Illes Balears Grant ES01/TCAI/24_2018Ministerio de Ciencia e innovación MCIN/AEI/10.13039/501100011033 (RTC2019-007399-1)Ministerio de Economía y Competitividad DI-17-09187Ministry of Economic Development Fondo per la Crescita Sostenibile- Sportello "Agrifood" PON I&C 2014-2020; Regione Campa-nia-"Sviluppo di una tecnologia Intelli- gente contro spoilage ed agenti patogeni: dal peptide an-timicrobico ad un PACKaging innovativo nella filiera ittica del MediMinistry of Economic Development "Packaging Bioattivi e bIOsanitizzanti: Sviluppo di stratEgie iNnovaTIve ed ecososteNibili pEr L'Industria Alimentare- (BIO-SENTINEL) project, grant number F/200092/01-03/X45Regione Campania Packaging innovativi a base di pEptidi antimicRobici per la SIcurezza Alimentare" (PERSIA) project, grant number POR FESR CAMPANIA 2014/2020 n. B63D18000530007
6 · The paper itself

Abstract

Since penicillin was discovered, antibiotics have been critical in the fight against infections. However, antibiotic misuse has led to drug resistance, which now constitutes a serious health problem. In this context, antimicrobial peptides (AMPs) constitute a natural group of short proteins, varying in structure and length, that act against certain types of bacterial pathogens. The antimicrobial peptide 1018-K6 (VRLIVKVRIWRR- NH2) has significant bactericidal and antibiofilm activity against

Indexed as

Antimicrobial Cationic PeptidesListeria monocytogenesAnti-Bacterial AgentsAntimicrobial PeptidesEscherichia coliEukaryotaLipidsLiposomesMicrobial Sensitivity TestsPenicillinsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesAntimicrobial PeptidesLipidsLiposomesPenicillinsantimicrobial peptidefood preservationmembrane lipid therapy (melitherapy)Salmonella spp.Staphylococcus spp.

Identifiers

PMID36293249
PMCPMC9603936
OpenAlexW4306385743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.