Evidence map›Paper›PMID 36293224›Full record

ArticleInternational journal of molecular sciences2022

Discovery of Simple Diacylhydrazine-Functionalized Cinnamic Acid Derivatives as Potential Microtubule Stabilizers.

Xiang Zhou, Yi-Hong Fu, Ya-Yu Zou, Jiao Meng, Gui-Ping Ou-Yang, Qiang-Sheng Ge, Zhen-Chao Wang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
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  5. Future medicinal chemistry · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiang ZhouState Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R & D of Fine Chemicals, Guizhou University, Guiyang 550025, China.ORCID 0000-0002-3589-9074
Yi-Hong FuScience and Technology College, Hubei University of Arts and Science, Xiangyang 441025, China.
Ya-Yu ZouCollege of Pharmacy, Guizhou University, Guiyang 550025, China.
Jiao MengState Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R & D of Fine Chemicals, Guizhou University, Guiyang 550025, China.
Gui-Ping Ou-YangCollege of Pharmacy, Guizhou University, Guiyang 550025, China.
Qiang-Sheng GeCollege of Pharmacy, Guizhou University, Guiyang 550025, China.
Zhen-Chao WangState Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R & D of Fine Chemicals, Guizhou University, Guiyang 550025, China.
Guizhou University · CNHubei University of Arts and Science · CN

Funding

Frontiers Science Center for Asymmetric Synthesis and Medicinal Molecules, Department of Edu-cation, Guizhou Province [Qianjiaohe KY number (2020)004]GZU (Guizhou University) Found for Newly Enrolled Talent No. 202229National Innovation and Entrepreneurship Training Program for College Students 2020033National Natural Science Foundation of China 22007022National Natural Science Foundation of China 32160661Program of Introducing Talents of Discipline to Universities of China (111 Program, D20023)Science and Technology Foundation of Guizhou Province [ZK[2021]034]
6 · The paper itself

Abstract

To develop novel microtubule-binding agents for cancer therapy, an array of

Indexed as

Antineoplastic AgentsTubulinCell Line, TumorCell ProliferationDose-Response Relationship, DrugDrug Screening Assays, AntitumorHydrazinesMicrotubulesMolecular StructureStructure-Activity RelationshipTubulin ModulatorsAntineoplastic AgentsHydrazinesTubulinTubulin Modulatorsantiproliferative activitycinnamic acid derivativesmicrotubuletubulin stabilizer

Identifiers

PMID36293224
PMCPMC9604255
OpenAlexW4306385492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.