Evidence map›Paper›PMID 36293153›Full record

ArticleInternational journal of molecular sciences2022

Lynch Syndrome Identification in Saudi Cohort of Endometrial Cancer Patients Screened by Universal Approach.

Rong Bu, Abdul K Siraj, Sandeep Kumar Parvathareddy, Kaleem Iqbal, Saud Azam, Zeeshan Qadri, Maha Al-Rasheed, Wael Haqawi, Mark Diaz, Khadija Alobaisi and 7 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Rong BuHuman Cancer Genomic Research, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia.ORCID 0000-0002-6853-1049
Abdul K SirajHuman Cancer Genomic Research, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia.
Sandeep Kumar ParvathareddyHuman Cancer Genomic Research, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia.
Kaleem IqbalHuman Cancer Genomic Research, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia.ORCID 0000-0001-5634-5030
Saud AzamHuman Cancer Genomic Research, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia.
Zeeshan QadriHuman Cancer Genomic Research, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia.
Maha Al-RasheedHuman Cancer Genomic Research, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia.
Wael HaqawiHuman Cancer Genomic Research, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia.
Mark DiazHuman Cancer Genomic Research, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia.
Khadija AlobaisiHuman Cancer Genomic Research, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia.
Padmanaban AnnaiyappanaiduHuman Cancer Genomic Research, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia.
Nabil SirajHuman Cancer Genomic Research, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia.
Hamed AlHusainiDepartment of Medical Oncology, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia.
Osama AlomarDepartment of Obstetrics-Gynecology, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia.ORCID 0000-0003-4715-9396
Ismail A Al-BadawiDepartment of Obstetrics-Gynecology, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia.
Fouad Al-DayelDepartment of Pathology, King Faisal Specialist Hospital and Research Centre, Riyadh 11211, Saudi Arabia.
Khawla S Al-KurayaHuman Cancer Genomic Research, Research Center, King Faisal Specialist Hospital and Research Center, Riyadh 11211, Saudi Arabia.ORCID 0000-0002-4126-3419
King Faisal Specialist Hospital & Research Centre · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lynch syndrome (LS) is the most common cause of inherited endometrial cancer (EC). The prevalence and molecular characteristic of LS in Middle Eastern women with EC have been underexplored. To evaluate the frequency of LS in a cohort of EC patients from Saudi Arabia, a total of 436 EC cases were screened utilizing immunohistochemistry (IHC),

Indexed as

Colorectal Neoplasms, Hereditary NonpolyposisEndometrial NeoplasmsDNA MethylationDNA Mismatch RepairFemaleGerm-Line MutationHumansMicrosatellite InstabilityMutS Homolog 2 ProteinSaudi ArabiaMutS Homolog 2 Proteinendometrial cancergermline mutationsLynch-like syndromeLynch syndromemismatch repair-deficientsomatic mutationsuniversal screening

Identifiers

PMID36293153
PMCPMC9603045
OpenAlexW4306385409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.