Evidence map›Paper›PMID 36293152›Full record

ArticleInternational journal of molecular sciences2022

Thermofluor-Based Optimization Strategy for the Stabilization of Recombinant Human Soluble Catechol-

Ana M Gonçalves, Augusto Q Pedro, Diana M Oliveira, Adriana E Oliveira, Marino F A Santos, Márcia A S Correia, João A Queiroz, Eugénia Gallardo, Maria J Romão, Luís A Passarinha

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ana M GonçalvesCICS-UBI-Health Sciences Research Centre, University of Beira Interior, 6201-506 Covilhã, Portugal.
Augusto Q PedroChemistry Department, CICECO-Aveiro Institute of Materials, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal.
Diana M OliveiraCICS-UBI-Health Sciences Research Centre, University of Beira Interior, 6201-506 Covilhã, Portugal.
Adriana E OliveiraCICS-UBI-Health Sciences Research Centre, University of Beira Interior, 6201-506 Covilhã, Portugal.
Marino F A SantosAssociate Laboratory i4HB-Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2819-516 Caparica, Portugal.ORCID 0000-0002-8205-1041
Márcia A S CorreiaAssociate Laboratory i4HB-Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2819-516 Caparica, Portugal.
João A QueirozCICS-UBI-Health Sciences Research Centre, University of Beira Interior, 6201-506 Covilhã, Portugal.ORCID 0000-0002-3096-8325
Eugénia GallardoCICS-UBI-Health Sciences Research Centre, University of Beira Interior, 6201-506 Covilhã, Portugal.ORCID 0000-0002-1802-8998
Maria J RomãoAssociate Laboratory i4HB-Institute for Health and Bioeconomy, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2819-516 Caparica, Portugal.ORCID 0000-0002-3004-0543
Luís A PassarinhaCICS-UBI-Health Sciences Research Centre, University of Beira Interior, 6201-506 Covilhã, Portugal.ORCID 0000-0001-6910-7576
University of Beira Interior · PTUniversidade Nova de Lisboa · PTUniversity of Aveiro · PT

Funding

COMPETE 2020-Programa Operacional Competitividade e Internacionalização IL2BioPro"-PTDC/BII-BBF/30840/2017European Regional Development Fund Centro-01-0145-FEDER-000019-C4-Centro de Competências em Cloud ComputingFundação para a Ciência e Tecnologia UIDB/00709/2020; UIDP/00709/2020; UIDB/50011/2020; UIDP/50011/2020;UIDB/04378/2020; UIDP/04378/2020; LA/P/0006/2020; LA/P/0140/2020; SFRH/BD/147519/2019; CEEC-IND/02599/2020; SFRH/BSAB/150376/2019
6 · The paper itself

Abstract

Catechol-

Indexed as

Carboxy-LyasesIonic LiquidsParkinson DiseaseCatechol O-MethyltransferaseCatecholsCysteineDopamineEstrogensGlycerolHumansLevodopaMetanephrineTrehaloseCarboxy-LyasesCatechol O-MethyltransferaseCatecholsCysteineDopamineEstrogensGlycerolIonic LiquidsLevodopaMetanephrineTrehaloseprotein activityprotein stabilitysoluble catechol-O-methyltransferase (SCOMT)thermal shift assay (TSA)

Identifiers

PMID36293152
PMCPMC9603843
OpenAlexW4306385343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.