Evidence map›Paper›PMID 36293083›Full record

ReviewInternational journal of molecular sciences2022

Biological Activity of Different Forms of Oxidized Parathyroid Hormone.

Ahmed A Hasan, Carl-Friedrich Hocher, Burkhard Kleuser, Bernhard K Krämer, Berthold Hocher

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Association between CKD-MBD and mortality in older patients with advanced CKD-results from the EQUAL study.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Ahmed A HasanInstitute of Pharmacy, Freie Universität Berlin, 14195 Berlin, Germany.ORCID 0000-0002-0382-4916
Carl-Friedrich HocherInstitute of Pharmacy, Freie Universität Berlin, 14195 Berlin, Germany.
Burkhard KleuserInstitute of Pharmacy, Freie Universität Berlin, 14195 Berlin, Germany.ORCID 0000-0002-1888-9595
Bernhard K KrämerFifth Department of Medicine (Nephrology/Endocrinology/Rheumatology/Pneumology), University Medical Centre Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Berthold HocherInstitute of Pharmacy, Freie Universität Berlin, 14195 Berlin, Germany.ORCID 0000-0001-8143-0579
Heidelberg University · DEFreie Universität Berlin · DEHunan Normal University · CNUniversity of Mannheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preclinical studies have shown that parathyroid hormone (PTH) loses its biological effects through oxidation. PTH can be oxidized at methionines 8 and 18. Three possible variations of oxidized PTH (oxPTH) exist: Met8(ox)PTH, Met18(ox)PTH, and Met8, Met18(di-ox)PTH. A recent study showed that Met18(ox)PTH retained biological activity and was able to upregulate

Indexed as

Parathyroid HormoneRenal Insufficiency, ChronicHumansMethionineOxidation-ReductionProspective StudiesMethionineParathyroid Hormonechronic kidney disease-mineral bone disorder (CKD-MBD)oxidative stressparathyroid hormone

Identifiers

PMID36293083
PMCPMC9603367
OpenAlexW4306152004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.