Evidence map›Paper›PMID 36293075›Full record

ArticleInternational journal of molecular sciences2022

Altered Circulating Follicular T Helper Cell Subsets and Follicular T Regulatory Cells Are Indicators of a Derailed B Cell Response in Lupus, Which Could Be Modified by Targeting IL-21R.

Krisztina Szabó, Ilona Jámbor, Kitti Pázmándi, Nikolett Nagy, Gábor Papp, Tünde Tarr

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Importance of B cells (Review).International journal of molecular medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Krisztina SzabóDivision of Clinical Immunology, Institute of Internal Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0002-0079-3659
Ilona JámborDivision of Clinical Immunology, Institute of Internal Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Kitti PázmándiDepartment of Immunology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0001-7709-6707
Nikolett NagyDivision of Clinical Immunology, Institute of Internal Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Gábor PappDivision of Clinical Immunology, Institute of Internal Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0002-8843-190X
Tünde TarrDivision of Clinical Immunology, Institute of Internal Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
University of Debrecen · HU

Funding

National Research, Development and Innovation Office (Hungary) K124177National Research, Development and Innovation Office (Hungary) PD121327New National Excellence Program of the Ministry for Innovation and Technology (National Research, Development and Innovation Office) and János Bolyai Research Scholarship (Hungarian Academy of Sciences) ÚNKP-21-05-DE-170
6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) is characterized by the breakdown of self-tolerance, the production of high-affinity pathogenic autoantibodies and derailed B cell responses, which indicates the importance of central players, such as follicular T helper (T

Indexed as

Lupus Erythematosus, SystemicReceptors, Interleukin-21Antibodies, MonoclonalAutoantibodiesComplement C4HumansT-Lymphocytes, Helper-InducerT-Lymphocytes, RegulatoryAntibodies, MonoclonalAutoantibodiesComplement C4Receptors, Interleukin-21B cellchemokine receptorsfollicular T helper cellfollicular T regulatory cellinterleukin-21 receptorsystemic lupus erythematosus

Identifiers

PMID36293075
PMCPMC9602506
OpenAlexW4306152372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.