Evidence map›Paper›PMID 36293064›Full record

ReviewInternational journal of molecular sciences2022

Wnt Signaling and Aging of the Gastrointestinal Tract.

Naoki Asano, Akio Takeuchi, Akira Imatani, Masashi Saito, Xiaoyi Jin, Waku Hatta, Kaname Uno, Tomoyuki Koike, Atsushi Masamune

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Role of T-box transcription factor 3 in gastric cancers.World journal of gastrointestinal pathophysiology · 2023
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Naoki AsanoDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.ORCID 0000-0003-4452-8459
Akio TakeuchiDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Akira ImataniDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Masashi SaitoDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Xiaoyi JinDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Waku HattaDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Kaname UnoDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.ORCID 0000-0002-4739-8795
Tomoyuki KoikeDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.ORCID 0000-0001-6472-3257
Atsushi MasamuneDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.ORCID 0000-0001-7184-7282
Tohoku University · JP

Funding

Japanese Society for the Promotion of Science 18K07928 and 19K08411
6 · The paper itself

Abstract

Aging is considered a risk factor for various diseases including cancers. In this aging society, there is an urgent need to clarify the molecular mechanisms involved in aging. Wnt signaling has been shown to play a crucial role in the maintenance and differentiation of tissue stem cells, and intensive studies have elucidated its pivotal role in the aging of neural and muscle stem cells. However, until recently, such studies on the gastrointestinal tract have been limited. In this review, we discuss recent advances in the study of the role of Wnt signaling in the aging of the gastrointestinal tract and aging-related carcinogenesis.

Indexed as

Wnt ProteinsWnt Signaling Pathwaybeta CateninCell DifferentiationGastrointestinal Tractbeta CateninWnt Proteinsagingbeta-cateninstem cellstem cell agingstomachWnt

Identifiers

PMID36293064
PMCPMC9603545
OpenAlexW4306152033

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.