Evidence map›Paper›PMID 36293055›Full record

ArticleInternational journal of molecular sciences2022

In Vivo and In Silico Investigation of the Anti-Obesity Effects of

Dalia Elebeedy, Aml Ghanem, Asmaa Saleh, Mona H Ibrahim, Omkulthom Al Kamaly, Mohammed A S Abourehab, Mohamed A Ali, Ahmed I Abd El Maksoud, Mahmoud A El Hassab, Wagdy M Eldehna

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Selected Mesoamerican Crops - Anti-Obesity Potential and Health Promotion. A Review.Plant foods for human nutrition (Dordrecht, Netherlands) · 2024
    Review
  3. Review
  4. Inhibition Effect of Adipogenesis and Lipogenesis via Activation ofInternational journal of molecular sciences · 2023
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 2 countries.

Dalia ElebeedyPharmaceutical Biotechnology Department, College of Biotechnology, Misr University for Science and Technology (MUST), 6th of October City 12573, Egypt.ORCID 0000-0003-4465-2556
Aml GhanemSchool of Biotechnology, Badr University in Cairo, Cairo 11829, Egypt.
Asmaa SalehDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.
Mona H IbrahimDepartment of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy for Girls, Al-Azhar University, Cairo 11754, Egypt.ORCID 0000-0002-8235-5715
Omkulthom Al KamalyDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.ORCID 0000-0003-4706-4311
Mohammed A S AbourehabDepartment of Pharmaceutics, Faculty of Pharmacy, Umm Al-Qura University, P.O. Box 21961, Makkah 24382, Saudi Arabia.ORCID 0000-0003-1348-6567
Mohamed A AliSchool of Biotechnology, Badr University in Cairo, Cairo 11829, Egypt.ORCID 0000-0002-7390-8592
Ahmed I Abd El MaksoudIndustrial Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, Sadat City 32897, Egypt.
Mahmoud A El HassabDepartment of Medicinal Chemistry, Faculty of Pharmacy, King Salman International University (KSIU), South Sinai 46612, Egypt.ORCID 0000-0002-6795-4816
Wagdy M EldehnaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33511, Egypt.ORCID 0000-0001-6996-4017
Badr University in Cairo · EGPrincess Nourah bint Abdulrahman University · SAAl-Azhar University · EGKafrelsheikh University · EGKing Salman International UniversityMisr University for Science and Technology · EGUmm al-Qura University · SAUniversity of Sadat City · EG

Funding

Princess Nourah bint Abdulrahman University PNURSP2022R141Umm al-Qura University 22UQU4290565DSR08
6 · The paper itself

Abstract

The increasing prevalence of obesity has become a demanding issue in both high-income and low-income countries. Treating obesity is challenging as the treatment options have many limitations. Recently, diet modification has been commonly applied to control or prevent obesity and its risks. In this study, we investigated novel therapeutic approaches using a combination of a potential probiotic source with prebiotics. Forty-eight adult male Sprague-Dawley rats were selected and divided into seven groups (eight rats per group). The first group was fed a high-fat diet, while the second group was a negative control. The other five groups were orally administered with a probiotic,

Indexed as

ChitosanHyperlipidemiasAnimalsCatalaseDiet, High-FatInflammationMaleMalondialdehydeObesityRatsRats, Sprague-DawleySeedsSuperoxide DismutaseTeaCatalaseChitosanMalondialdehydeSuperoxide DismutaseTeachia seedschitosandockinggreen teaLactiplantibacillus plantarumnutritionobesityprebiotics

Identifiers

PMID36293055
PMCPMC9602495
OpenAlexW4306152255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.