Evidence map›Paper›PMID 36292993›Full record

ReviewInternational journal of molecular sciences2022

Pathogenesis of Port-Wine Stains: Directions for Future Therapies.

Lian Liu, Xiaoxue Li, Qian Zhao, Lihua Yang, Xian Jiang

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Laser and light-based treatments for port-wine birthmarks - a systematic review and network meta-analysis.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Pooled it
  2. Pooled it
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  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Photo-Mediated Ultrasound Therapy (PUT) for the Treatment of Deep Cutaneous Vasculature.IEEE open journal of ultrasonics, ferroelectrics, and frequency control · 2025
    Article
  14. EndothelialFrontiers in cell and developmental biology · 2025
    Article
  15. Article
  16. Review
  17. Sturge weber syndrome: A case report.Clinical case reports · 2024
    Article
  18. Article
  19. Sturge-Weber syndrome: an update for the pediatrician.World journal of pediatrics : WJP · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lian LiuDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu 610017, China.
Xiaoxue LiDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu 610017, China.
Qian ZhaoDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu 610017, China.
Lihua YangDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu 610017, China.
Xian JiangDepartment of Dermatology, West China Hospital, Sichuan University, Chengdu 610017, China.ORCID 0000-0001-5109-6055
Sichuan University · CN

Funding

Department of Science and Technology of Sichuan Province 2021YJ0426National Natural Science Foundation of China 82003373 and 82073473Post-Doctor Research Project and the 1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University 2020HXBH058 and ZYJC21036
6 · The paper itself

Abstract

Port-wine stains (PWSs) are congenital vascular malformations that involve the skin and mucosa. To date, the mechanisms underlying the pathogenesis and progression of PWSs are yet to be clearly elucidated. The potential reasons for dilated vessels are as follows: (1) somatic

Indexed as

Port-Wine StainAngiopoietin-2AxitinibEphrin-B2HumansImiquimodPhosphatidylinositol 3-KinasesPhotosensitizing AgentsProto-Oncogene Proteins c-aktReceptor, EphA1Ribosomal Protein S6 Kinases, 70-kDaSirolimusTreatment OutcomeVascular Endothelial Growth Factor Receptor-2Angiopoietin-2AxitinibEphrin-B2ImiquimodPhosphatidylinositol 3-KinasesPhotosensitizing AgentsProto-Oncogene Proteins c-aktReceptor, EphA1Ribosomal Protein S6 Kinases, 70-kDaSirolimusVascular Endothelial Growth Factor Receptor-2pathogenesisport-wine staintreatment

Identifiers

PMID36292993
PMCPMC9603382
OpenAlexW4304689759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.