Evidence map›Paper›PMID 36292932›Full record

ArticleInternational journal of molecular sciences2022

Design of Cyclic Peptide-Based Nanospheres and the Delivery of siRNA.

Junfeng Ke, Jingli Zhang, Junyang Li, Junqiu Liu, Shuwen Guan

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Junfeng KeSchool of Life Sciences, Jilin University, Changchun 130012, China.
Jingli ZhangSchool of Life Sciences, Jilin University, Changchun 130012, China.
Junyang LiSchool of Life Sciences, Jilin University, Changchun 130012, China.ORCID 0000-0002-2953-3535
Junqiu LiuState Key laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China.ORCID 0000-0003-1608-7908
Shuwen GuanSchool of Life Sciences, Jilin University, Changchun 130012, China.ORCID 0000-0001-8235-933X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, cyclic peptides have attracted much attention due to their chemical and enzymatic stability, low toxicity, and easy modification. In general, the self-assembled nanostructures of cyclic peptides tend to form nanotubes in a cyclic stacking manner through hydrogen bonding. However, studies exploring other assembly strategies are scarce. In this context, we proposed a new assembly strategy based on cyclic peptides with covalent self-assembly. Here, cyclic peptide-(DPDPDP) was rationally designed and used as a building block to construct new assemblies. With cyclo-(DP)

Indexed as

NanospheresNanostructuresNanotubesPeptides, CyclicRNA, Small InterferingPeptides, CyclicRNA, Small Interferingcovalent assemblycyclopeptidesnanospheresRNAi

Identifiers

PMID36292932
PMCPMC9602810

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.