Evidence map›Paper›PMID 36292874›Full record

ReviewInsects2022

Recent Insights into Insect Olfactory Receptors and Odorant-Binding Proteins.

Tal Soo Ha, Dean P Smith

Open access · goldAbstract readReview
In one paragraph

Review in Insects, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. Silencing Attempts ofInsects · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Comparative Antennal Transcriptome Analysis ofInternational journal of molecular sciences · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Sex Differences in Antennal Transcriptome ofInternational journal of molecular sciences · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Identification of 2,4-Di-International journal of molecular sciences · 2023
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Tal Soo HaDepartment of Biomedical Science, College of Natural Science, Daegu University, Gyeongsan 38453, Gyeongsangbuk-do, Korea.
Dean P SmithDepartments of Pharmacology and Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-4271-0436
Daegu University · KRThe University of Texas Southwestern Medical Center · US

Funding

Aminophospholipid Signaling in Olfactory TransductionR01DC015230 · NIDCD · UT SOUTHWESTERN MEDICAL CENTER · PI SMITH, DEAN P. · 2017 to 2021
$1.7M
NIDCD NIH HHS R01 DC015230NIH HHS R01 DC015230
6 · The paper itself

Abstract

Human and insect olfaction share many general features, but insects differ from mammalian systems in important ways. Mammalian olfactory neurons share the same overlying fluid layer in the nose, and neuronal tuning entirely depends upon receptor specificity. In insects, the olfactory neurons are anatomically segregated into sensilla, and small clusters of olfactory neurons dendrites share extracellular fluid that can be independently regulated in different sensilla. Small extracellular proteins called odorant-binding proteins are differentially secreted into this sensillum lymph fluid where they have been shown to confer sensitivity to specific odorants, and they can also affect the kinetics of the olfactory neuron responses. Insect olfactory receptors are not G-protein-coupled receptors, such as vertebrate olfactory receptors, but are ligand-gated ion channels opened by direct interactions with odorant molecules. Recently, several examples of insect olfactory neurons expressing multiple receptors have been identified, indicating that the mechanisms for neuronal tuning may be broader in insects than mammals. Finally, recent advances in genome editing are finding applications in many species, including agricultural pests and human disease vectors.

Indexed as

disease vectorodorant-binding proteinsodorant receptorsolfactionolfactory neurons

Identifiers

PMID36292874
PMCPMC9604063
OpenAlexW4306151993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.