Evidence map›Paper›PMID 36292769›Full record

ArticleGenes2022

Host Genetic Risk Factors Associated with COVID-19 Susceptibility and Severity in Vietnamese.

Vu Phuong Nhung, Nguyen Dang Ton, Tran Thi Bich Ngoc, Ma Thi Huyen Thuong, Nguyen Thi Thanh Hai, Kim Thi Phuong Oanh, Le Thi Thu Hien, Pham Ngoc Thach, Nong Van Hai, Nguyen Hai Ha

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Genetic variants inFrontiers in genetics · 2025
    Article
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  8. Participation of Single-Nucleotide Variants inPathogens (Basel, Switzerland) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Vu Phuong NhungInstitute of Genome Research, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi 100000, Vietnam.
Nguyen Dang TonInstitute of Genome Research, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi 100000, Vietnam.ORCID 0000-0003-0182-8996
Tran Thi Bich NgocInstitute of Genome Research, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi 100000, Vietnam.ORCID 0000-0002-4129-9024
Ma Thi Huyen ThuongInstitute of Genome Research, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi 100000, Vietnam.
Nguyen Thi Thanh HaiNational Hospital for Tropical Disease, Kim Chung, Dong Anh, Hanoi 100000, Vietnam.ORCID 0000-0003-2809-1859
Kim Thi Phuong OanhInstitute of Genome Research, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi 100000, Vietnam.
Le Thi Thu HienInstitute of Genome Research, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi 100000, Vietnam.
Pham Ngoc ThachNational Hospital for Tropical Disease, Kim Chung, Dong Anh, Hanoi 100000, Vietnam.
Nong Van HaiInstitute of Genome Research, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi 100000, Vietnam.ORCID 0000-0003-2939-8430
Nguyen Hai HaInstitute of Genome Research, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi 100000, Vietnam.ORCID 0000-0002-5431-5935
Vietnam Academy of Science and Technology · VNHanoi Medical University · VNHospital for Tropical Diseases · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the emergence and rapid transmission of SARS-CoV-2, numerous scientific reports have searched for the association of host genetic variants with COVID-19, but the data are mostly acquired from Europe. In the current work, we explored the link between host genes (SARS-CoV-2 entry and immune system related to COVID-19 sensitivity/severity) and ABO blood types with COVID-19 from whole-exome data of 200 COVID-19 patients and 100 controls in Vietnam. The O blood type was found to be a protective factor that weakens the worst outcomes of infected individuals. For SARS-CoV-2 susceptibility, rs2229207 (TC genotype, allele C) and rs17860118 (allele T) of

Indexed as

COVID-19Asian PeopleHumansMembrane Transport ProteinsRisk FactorsSARS-CoV-2VietnamMembrane Transport ProteinsSLC6A20 protein, humanABO blood typeCOVID-19host genetic variantsSARS-CoV-2whole-exome sequencing

Identifiers

PMID36292769
PMCPMC9601961
OpenAlexW4306742619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.