Evidence map›Paper›PMID 36292759›Full record

ArticleGenes2022

Different Mechanisms Cause Hypomethylation of Both

Francesco Passaretti, Laura Pignata, Giuseppina Vitiello, Viola Alesi, Gemma D'Elia, Francesco Cecere, Fabio Acquaviva, Daniele De Brasi, Antonio Novelli, Andrea Riccio and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Francesco PassarettiDepartment of Molecular Medicine and Medical Biotechnology, Università degli Studi di Napoli Federico II, 80131 Naples, Italy.ORCID 0000-0002-6707-9847
Laura PignataDepartment of Environmental Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), Università degli Studi della Campania "Luigi Vanvitelli", 81100 Caserta, Italy.ORCID 0000-0001-8835-5567
Giuseppina VitielloU.O.C. Medical Genetics, Department of Translational Medical Sciences, A.O.U. Federico II, 80131 Naples, Italy.
Viola AlesiLaboratory of Medical Genetics, Translational Cytogenomics Research Unit, Bambino Gesù Children Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0001-7514-5683
Gemma D'EliaLaboratory of Medical Genetics, Translational Cytogenomics Research Unit, Bambino Gesù Children Hospital, IRCCS, 00165 Rome, Italy.
Francesco CecereDepartment of Environmental Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), Università degli Studi della Campania "Luigi Vanvitelli", 81100 Caserta, Italy.
Fabio AcquavivaU.O.S. Medical Genetics, Pediatrics of Chronic and Multifactorial Diseases, A.O.R.N. Santobono-Pausilipon, 80129 Naples, Italy.ORCID 0000-0001-9192-1232
Daniele De BrasiU.O.S. Medical Genetics, Pediatrics of Chronic and Multifactorial Diseases, A.O.R.N. Santobono-Pausilipon, 80129 Naples, Italy.
Antonio NovelliLaboratory of Medical Genetics, Translational Cytogenomics Research Unit, Bambino Gesù Children Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0002-9037-4297
Andrea RiccioDepartment of Environmental Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), Università degli Studi della Campania "Luigi Vanvitelli", 81100 Caserta, Italy.ORCID 0000-0001-7990-3576
Achille IolasconDepartment of Molecular Medicine and Medical Biotechnology, Università degli Studi di Napoli Federico II, 80131 Naples, Italy.ORCID 0000-0002-9558-0356
Flavia CerratoDepartment of Environmental Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), Università degli Studi della Campania "Luigi Vanvitelli", 81100 Caserta, Italy.ORCID 0000-0003-3794-3021
University of Campania "Luigi Vanvitelli" · ITBambino Gesù Children's Hospital · ITFederico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silver-Russell syndrome is an imprinting disorder characterised by pre- and post-natal growth retardation and several heterogeneous molecular defects affecting different human genomic loci. In the majority of cases, the molecular defect is the loss of methylation (LOM) of the

Indexed as

Silver-Russell SyndromeDNA Copy Number VariationsDNA MethylationGenomic ImprintingHumansPhenotype11p15.5 imprinted genes clusterdifferentially methylated regionsDNA methylation defectsimprinting disordersmicroduplicationSilver–Russell syndrome

Identifiers

PMID36292759
PMCPMC9602374
OpenAlexW4306377066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.