Evidence map›Paper›PMID 36292706›Full record

ArticleGenes2022

Autism with Epilepsy: A Neuropsychopharmacology Update.

Roberto Canitano, Roberto Palumbi, Valeria Scandurra

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Diverse excess GABA modes drive autism and epilepsy-autism comorbidity.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Observational
  6. Review
  7. Review
  8. Treatment options in autism with epilepsy.Frontiers in child and adolescent psychiatry · 2024
    Article
  9. Autism with co-occurring epilepsy care pathway in Europe.European psychiatry : the journal of the Association of European Psychiatrists · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Roberto CanitanoDivision of Child and Adolescent Neuropsychiatry, University Hospital of Siena, 53100 Siena, Italy.
Roberto PalumbiBasic Medical Sciences, Neurosciences, and Sensory Organs Department, University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0003-4077-5700
Valeria ScandurraDivision of Child and Adolescent Neuropsychiatry, University Hospital of Siena, 53100 Siena, Italy.
University of Siena · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between autism spectrum disorders (ASD) and epilepsy has been extensively documented, and the estimated prevalence varies depending upon the selected population and the clinical characteristics. Currently, there are a lack of studies assessing the patient care pathways in ASD, particularly for comorbidity with epilepsy, despite its personal, familial, and economic impacts. Genetic abnormalities are likely implicated in the association of ASD and epilepsy, although they are currently detectable in only a small percentage of patients, and some known genetic and medical conditions are associated with ASD and epilepsy. There is no specificity of seizure type to be expected in children and adolescents with ASD compared with other neurodevelopmental disorders or epileptic syndromes. Treatment options include antiepileptic drugs (AED) and developmentally-based early interventions for ASD. Carbamazepine and lamotrigine are the most used AED, but further studies are needed to more precisely define the most suitable medications for this specific group of children with ASD.

Indexed as

Autistic DisorderEpilepsyAdolescentAnticonvulsantsCarbamazepineChildHumansLamotrigineAnticonvulsantsCarbamazepineLamotrigineautismchild and adolescentepilepsytreatment

Identifiers

PMID36292706
PMCPMC9601574
OpenAlexW4303685862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.