Evidence map›Paper›PMID 36292673›Full record

ArticleGenes2022

Bta-miR-6531 Regulates Calcium Influx in Bovine Leydig Cells and Is Associated with Sperm Motility.

Qiang Ding, Xiuhu Ding, Shuwen Xia, Fang Zhao, Kunlin Chen, Yong Qian, Shaoxian Cao, Zhiping Lin, Yundong Gao, Huili Wang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Qiang DingInstitute of Animal Science, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Xiuhu DingCollege of Animal Science & Technology, Nanjing Agricultural University, Nanjing 210095, China.
Shuwen XiaInstitute of Animal Science, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Fang ZhaoInstitute of Animal Science, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Kunlin ChenInstitute of Animal Science, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Yong QianInstitute of Animal Science, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Shaoxian CaoInstitute of Animal Science, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Zhiping LinJiangsu Youyuan Dairy Research Institute Co., Ltd., Nanjing 211106, China.
Yundong GaoShandong OX Livestock Breeding Co., Ltd., Jinan 250131, China.
Huili WangInstitute of Animal Science, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Jifeng ZhongKey Laboratory of Crop and Animal Integrated Farming, Ministry of Agriculture and Rural Affairs, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Ministry of Agriculture and Rural Affairs · CNJiangsu Academy of Agricultural Sciences · CNNanjing Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) play key roles in sperm as the regulatory factors involved in fertility and subsequent early embryonic development. Bta-miR-6531 is specifically a highly enriched miRNA in low-motility sperms in previous study. To investigate the mechanism of bta-miR-6531, 508 shared target genes of bta-miR-6531 were predicted using two miRNA target databases (TargetScan7 and miRWalk). According to the Kyoto Encyclopedia of Genes and Genomes (KEGG), the calcium and cAMP signaling pathways were the most enriched of the target genes. A dual-luciferase assay indicated that bta-miR-6531 targeted

Indexed as

CalciumMicroRNAsAnimalsCattleLeydig CellsMaleRNA, MessengerSemenSperm MotilityCalciumMicroRNAsRNA, MessengerATP2A2bta-miR-6531calcium signaling pathwaySNPsperm motility

Identifiers

PMID36292673
PMCPMC9601708
OpenAlexW4303685892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.