Evidence map›Paper›PMID 36292669›Full record

ArticleGenes2022

A Single Nucleotide Polymorphism (rs3811792) Affecting Human

Veronika Zámbó, Gabriella Orosz, Luca Szabó, Kinga Tibori, Szabolcs Sipeki, Krisztina Molnár, Miklós Csala, Éva Kereszturi

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Veronika ZámbóDepartment of Molecular Biology, Semmelweis University, H-1085 Budapest, Hungary.
Gabriella OroszDepartment of Molecular Biology, Semmelweis University, H-1085 Budapest, Hungary.
Luca SzabóDepartment of Molecular Biology, Semmelweis University, H-1085 Budapest, Hungary.ORCID 0000-0002-1907-9957
Kinga TiboriDepartment of Molecular Biology, Semmelweis University, H-1085 Budapest, Hungary.
Szabolcs SipekiDepartment of Molecular Biology, Semmelweis University, H-1085 Budapest, Hungary.
Krisztina MolnárDepartment of Molecular Biology, Semmelweis University, H-1085 Budapest, Hungary.
Miklós CsalaDepartment of Molecular Biology, Semmelweis University, H-1085 Budapest, Hungary.ORCID 0000-0002-3829-4361
Éva KereszturiDepartment of Molecular Biology, Semmelweis University, H-1085 Budapest, Hungary.ORCID 0000-0003-4778-3332
Semmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The combined prevalence of type 1 (T1DM) and type 2 (T2DM) diabetes mellitus is 10.5% worldwide and this is constantly increasing. The pathophysiology of the diseases include disturbances of the lipid metabolism, in which acyl-CoA desaturases play a central role as they synthesize unsaturated fatty acids, thereby providing protection against lipotoxicity. The stearoyl-CoA desaturase-5 (SCD5) isoform has received little scientific attention. We aimed to investigate the

Indexed as

Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2Case-Control StudiesCoenzyme AFatty AcidsFatty Acids, UnsaturatedHEK293 CellsHumansPolymorphism, Single NucleotidePromoter Regions, GeneticProtein IsoformsStearoyl-CoA DesaturaseTranscription FactorsCoenzyme AFatty AcidsFatty Acids, UnsaturatedProtein IsoformsSCD5 protein, humanStearoyl-CoA DesaturaseTranscription Factorsfatty acidlipid metabolismlipotoxicitymetabolic disordersingle nucleotide polymorphismstearoyl-CoA desaturase-5 (SCD5)type 1 diabetes mellitus (T1DM)type 2 diabetes mellitus (T2DM)

Identifiers

PMID36292669
PMCPMC9601412
OpenAlexW4303685903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.